purpose: to evaluate the efficacy of riboflavin administration and ultraviolet a (uva) cross-linking on advanced symptomatic bullous keratopathy (bk). methods: 10 patients with symptomatic pseudophakic bullous keratopathy (pbk) were included. slit-lamp examination, visual acuity, foreign body sensation (fbs) and corneal thickness as measured by pentacam, were performed before corneal cross-link...

in our previous work, the effect of use of a water soluble cdi/nhs system as nontoxic cross-linking agent on fabrication of gelatin nanoparticles was investigated. in this research, the effect of variation in some synthetic parameters of gelatin nanoparticles cross-linked by cdi/nhs system such as type of gelatin and formulation of cross- linking agent on their size and distribution was examine...

patients with keratoconus constitute a large proportion of patients suffering from anterior segment disorders. as of this time, however, its pathogenesis has not yet been elucidated. a reduction in cross-link between collagen molecules has been observed in keratoconic eyes as compared to normal ones. present approaches only address refractive errors resulting from the abnormal abnormal corneal ...

In this research, gelatin nanoparticles were synthesized via inverse miniemulsion method by employing a mixture of a water soluble carbodiimide (CDI) and N-hydroxysuccinimide (NHS) as a non-toxic cross-linking system. The gelatin nanoparticles were characterized for their size and size distribution, morphology and stability and were compared with those of nanoparticles cross-linked by glutarald...