Purpose of the study . To intensity lipid peroxidation (LPO) and indicators antioxidant protection in liver rats different sexes with combined pathology – growth Guerin's carcinoma presence experimental type 1 diabetes mellitus. Materials methods The levels malondialdehyde (MDA) diene conjugates (DC), activities superoxide dismutase (SOD) catalase, vitamins A D were studied by conventional spec...

Passive Heymann nephritis (PHN) is a model of human membranous nephropathy that is characterized by formation of granular subepithelial immune deposits in the glomerular capillary wall which results in complement activation. This is causally related to damage of the filtration barrier and subsequent proteinuria. The local accumulation of injurious reactive oxygen species (ROS) is a major effect...

Background Drug abuse among pregnant women continues at alarming frequency. Exposed children often show selective impairments of attention and other disturbances which might develop to major cognitive disorders. This work seeks to examine the impact of prenatal stress (PS) induced by the psychostimulant drug amphetamine (AMPH) on memory functions in male offspring of rats and to study the possi...

OBJECTIVE To explore the effects of Gymnadenia conopsea alcohol extract (GcAE) on the collagen synthesis in rat lungs exposed to silica and the influence on antioxidase activities, level of lipid peroxidation (LPO). METHODS One hundred and twenty rats were randomly divided into control group, silica group, and GcAE-treated group. Silicotic animal models were established by direct tracheal ins...

The methanol extract of Bauhinia racemosa Lam. (Caesalpiniaceae) stem bark was investigated for the antioxidant and hepatoprotective effects in Wistar albino rats. Different groups of animals were administered with paracetamol (500 mg/kg, (p.o.) once in a day for 7 days) and carbon tetrachloride (CCl4) (30 % CCl4, 1 ml/kg b.wt. in liquid paraffin 3 doses (i.p.) at 72 h interval). The methanol e...

Bacterial strain Vibrio sp. (PIGB 184) isolated from water samples of the Arabian Sea and identified through 16S rRNA demonstrated the production of pigmentary antioxidants with higher ABTS activities 90.9 ± 0.42 % in comparison with the standard commercial pigmented antioxidant, quercetin 88.8 ± 1.4 %. Antioxidative metabolites of this strain substantially inhibit the lipid peroxidation (LPO) ...

Most used in physiotherapy physical factors has an electromagnetic nature. Initially, the therapeutic effect of electromagnetic radiation in a wide range of frequencies associated with activation of metabolic processes in the exposed tissues. The most highly-absorbing ultra high frequency (UHF) energy of tissues are the blood, lymph, parenchymatous tissue, muscles. One of the most important fac...

The importance of free amino acids in the processes vital activity normal and pathological conditions is well known. At same time, there are no data on role blood plasma valine formation thyroid status, prooxidant-antioxidant state, development hyperthermia caused by bacterial endotoxin, although its participation these quite natural, since an inhibitor arginase, which affects level arginine ac...

Background: Paraquat (PQ) is one of the most important herbicides used in agriculture. Objectives: This study was conducted to compare preventive effect vitamin D (Vit D) and N-acetylcysteine (NAC) against kidney injury rats versus promotive PQ. Methods: In this study, were divided into six groups. The control group (group 1) received normal saline, Vit 2) intraperitoneal (IP) injections of+Vit...

We investigated the lipid-lowering effects of methanolic extract of Vernonia amygdalina (VA) leaves in rats fed an high cholesterol diet, and compared with a standard hypolipidemic drug, Questran (Qu). The effects of VA on the lipid profile were assessed by measuring the levels of total cholesterol, triglyceride, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) choleste...