نتایج جستجو برای: liposomal gene delivery
تعداد نتایج: 1330057 فیلتر نتایج به سال:
and encapsulation into lipid nanoparticles. [ 7 ] Therapeutic application of RNA interference (RNAi) requires delivery of siRNAs into the cytoplasm of targeted cells and tissues, where they are recognized and associated with RNA-induced silencing complex (RISC) to perform their function. [ 8 ] This rate-limiting delivery step has been dealt with by several approaches, such as co-encapsulation o...
The efficacy of polyion-complexes between charged liposomes and oppositely charged polymers for the oral delivery of therapeutic peptides and proteins has been reported previously. It was the aim of the current study, to investigate whether polyion-complexes between negatively charged liposomes and the cationic polymer poly(allylamine) (PALAM) can be formed. Furthermore, the protease inhibitory...
Many barriers to drug delivery into a tumor site require careful consideration when designing a new drug. In this study, the adhesive targeting and drug specificity of modified liposomal vesicles on human-scar-producing cells, keloid fibroblasts, were investigated. Keloids express abundant levels of mucopolysaccharides and receptor tyrosine kinase (RTK). In this report, the structural propertie...
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