the protective effect of liquorice plant extract (lpe) on ccl4-induced hepatotoxicity in common carp was evaluated using fifty adult carps. the fish were cultured in a standard environment in terms of water flow rate, oxygen, ph, food and temperature. the fish were assigned into 5 groups (n = 10) as control, sham, and tests. the test groups were pre-treated for 3 h with various concentrations o...

BACKGROUND Herpes Simplex Virus 1 (HSV-1) resistance to drugs and the side effects of drugs have drawn the attention of investigators to herbal plants. OBJECTIVES The main aim of the current research was to investigate the effects of Glycyrrhiza glabra (liquorice root) on HSV-1. One of the objectives of the current research was to determine the efficacy and the effect of the elapsed incubatio...

Glycyrrhiza glabra L. (family:Fabaceae:Leguminosae) is one of the important medicinal plant, commonly called as liquorice. Thirty-two Sprague-Dawley male rats were randomly distributed into four groups (n=8). Experimental groups were injected intra-peritoneally with aqueous extract of G. glabra at 50, 100 and 200 mg/kg/day, respectively, for 30 consecutive days while control group was injected ...

Cyclosporine (CyA) is a well-known immunosuppressant with a narrow therapeutic window. Its bioavailability is affected by many other traditional drugs and herbal extracts. Cytochrome P-450 isoenzymes CYP3A4 and CYP3A5 and protein P-glycoprotein (P-gp) are involved in CyA bioavailability. Interactions of CyA with herbal extracts are not well known, but, given their increased concomitant use, it ...

AIM To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori (H. pylori). METHODS Twenty-five plants were boiled in water to produce aqueous extracts that simulate the effect of cooking. The bactericidal activity of the extracts was assessed by a standard kill-curve with seven strains of H. pylori. The anti-adhesive property was assessed by the inh...

Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors;...

Whether drinking from a cup versus through straw effects sensory perception is inconclusive, as whether such differences hold across and within multiple sips. This study aimed to determine if product profiles discrimination varied depending on was sipped or straw. An expert panel (n = 9) investigated in temporal of six milkshakes sipping methods. Temporal eight attributes analyzed selected time...