BACKGROUND/AIMS The pathogenesis of non-alcoholic steatohepatitis (NASH) is poorly understood. Hepatic iron and copper overload can directly cause lipid peroxidation and eventually hepatic damage. The aim of this study was to investigate the role of hepatic iron and copper accumulation in the development of NASH. METHODS Fifty-three patients with NASH were studied. All patients underwent live...

During the last 16 years an increasing number of studies have indicated a new diagnostic marker of alcohol abuse, unrelated to any of the conventional markers of alcoholism. This marker, now called carbohydrate-deficient transferrin, consists mainly of one or two isoforms of transferrin that are deficient in their terminal trisaccharides. Such isoforms have so far been detected by methods based...

background: division of human genetics (dhg) is a referral center for karyotyping and counseling to the couples as well as to the individuals referred with bad obstetric history and infertility. materials and methods: from 1972 to 2003, overall 1666 couples and 131 female partners with bad obstetric history (boh) such as; spontaneous abortions, live births with congenital malformations and stil...

presence of extra roots and canals should be considered before initiation of root canal treatment for the success of endodontic treatment. a mandibular second premolar with three separate roots is very rare and its prevalence has been reported to be around 0.1%. this case report explains non-surgical endodontic treatment of a mandibular second premolar with three separate roots and three separa...

Background—Haemochromatosis is a common genetic disease leading to iron overload. Although the gene had been identified (HFE), the pathogenesis had not been fully elucidated. The inadvertent transplant of a C282Y homozygous liver and intestine provided a unique opportunity to study this problem. Methods—A 19 year old man underwent orthotopic liver and intestinal transplantation in January 1997 ...

Abstract Introduction/Objective Ectopic liver is a rare developmental abnormality, in which tissue localized outside the normal and has no connection to native liver. The presence of ectopic been reported most commonly gall bladder. Intrathoracic cavity, kidney, abdominal wall, esophagus are other sites where it identified. But its intraperitoneal rarely previously. We report such case young fe...