Liver cirrhosis is characterized by hepatic dysfunction with extensive accumulation of fibrous tissue in the liver. In response to chronic hepatic injury, hepatic portal myofibroblasts and activated hepatic stellate cells (HSCs) play a role in liver fibrosis. Although administration or gene expression of hepatocyte growth factor (HGF) leads to improvement in hepatic fibrosis/cirrhosis, the rela...

Cirrhosis is the final stage of chronic liver disease caused by fibrosis which decreases function and changes shape structure liver. Portal hypertension an essential pathophysiology cirrhosis, can lead to increased risk death in patients resulting very detrimental complications originating from portal obstruction blood flow, such as cirrhosis or blockage vessels. According EASL guidelines, non-...

Background: Diabetes mellitus is a metabolic condition comprising of irregularly elevated level blood glucose. There are several different types mellitus. Several studies show the association between and liver cirrhosis. Aim: To assess frequency diabetes in cirrhosis patients at tertiary care hospital Methodology: Our study was descriptive Cross-Sectional Study carried out Department Medicine, ...

The role of trace elements in the pathogenesis of liver cirrhosis and its complications is still not clearly understood. Serum concentrations of zinc, copper, manganese and magnesium were determined in 105 patients with alcoholic liver cirrhosis and 50 healthy subjects by means of plasma sequential spectrophotometer. Serum concentrations of zinc were significantly lower (median 0.82 vs. 11.22 m...

Serum C3 and C4 levels have been measured in healthy subjects and patients with hepatitis, cirrhosis of the liver and liver cancer. A significant elevation of serum C4 was found in liver cancer and reduction in cirrhosis. There was a direct correlation between bilirubin levels and C3 in hepatitis and serum albumin and C3 in cirrhosis. Serum C4 appears to be a more sensitive indicator of liver d...

background liver is prone to different diseases including metabolic, congenital, infections, drug injuries, and malignancies. liver biopsy is an aggressive but definitive way to diagnose liver diseases. objectives the present study is designed to evaluate the results of liver biopsies in children referred to the pediatric gastroenterology department of nemazee hospital. materials and methods th...

Some recent studies have found regression of liver cirrhosis after antiviral therapy in patients with hepatitis C virus (HCV)-related liver cirrhosis, but there have been no reports of complete regression of esophageal varices after interferon/peg-interferon and ribavirin combination therapy. We describe two cases of complete regression of esophageal varices and splenomegaly after interferon-al...

Unsafe use of alcohol results in approximately 2.5 million deaths worldwide, with cirrhosis contributing to 16.6% of reported deaths. Serum insulin levels are often elevated in alcoholism and may result in diabetes, which is why alcoholic liver disease and diabetes often are present together. Because there is a sizable population with these diseases alone or in combination, the purpose of this ...

BACKGROUND Hepatic encephalopathy has a negative impact on health-related quality of life (QoL) in liver cirrhosis. There are scarce and conflicting data on whether type or etiology of liver cirrhosis could be related to hepatic encephalopathy in patients with cirrhosis. We aimed to determine the impact of cirrhosis etiology on hepatic encephalopathy and whether hepatic encephalopathy affects h...

Ultrasound images are widely used for diagnosis of liver cirrhosis. In liver cirrhosis classification using Mmode ultrasound images, Zhou’s method has been shown to be effective. However, in Zhou’s approach, the liver cirrhosis classification performance depends on the accuracy of the abdominal aorta wall extraction. Therefore, we examine to classify the liver cirrhosis not using the abdominal ...