نتایج جستجو برای: liver histology

تعداد نتایج: 354421  

Journal: :Bioscientist 2022

Turmeric (Curcuma longa L.) rhizome contains antioxidant compounds that can prevent damage to the liver. Thioacetamide (TAA) is an organosulfur compound in form of crystals and widely used as a fungicide organic solvent textile, leather paper industries, well being motor fuel stabilizer. Continuous exposure TAA cause hepatocyte parenchymatous degeneration necrosis. The purpose this study was de...

Background: Acantholimon gilliati Turril(Plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of Iran. Aim of the study: To investigate the hepatoprotective effect of methanoilc extract (ME) of A. gilliati on formaldehyde (FA) induced liver injury in adult male mice.Materials and methods: Fifty six adult male mice were divided into 8 groups. In control gr...

Journal: :Nutricion hospitalaria 2014
Rubén Díez Rodríguez María D Ballesteros Pomar Alicia Calleja Fernández Sara Calleja Antolin Isidoro Cano Rodríguez Pedro Linares Torres Francisco Jorquera Plaza José Luis Olcoz Goñi

BACKGROUND Morbidly obese patients usually present vitamin D deficiency or secondary hyperparathyroidism. Low vitamin D levels have been recently related to non-alcoholic fatty liver disease (NAFLD). The aim of this study was to analyse the relationship between vitamin D, bone turnover markers and non-alcoholic fatty liver disease and metabolic syndrome in severely obese patients. METHODS One...

2017
Chen-wei Pan Shou-xing Yang Zhen-zhen Pan Bo Zheng Jian-zhang Wang Guang-rong Lu Zhan-xiong Xue Chang-long Xu

Andrographolide (ADH), a diterpenoid lactone extracted from Andrographis paniculata, has been found to have anti-inflammatory and anti-oxidative effects. However, its protective effects and mechanisms on liver injury have not been investigated clearly. This study takes an attempt to reveal the protective effects and mechanism of ADH on lipopolysaccharide (LPS) and D-galactosamine (D-GalN)-induc...

Journal: :International Journal of Travel Medicine and Global Health 2015

2013
Virginia Fernández Romina Vargas Valentina Castillo Nicolás Cádiz Daniela Bastías Sebastián Román Gladys Tapia Luis A. Videla

The role of iron (Fe)-induced prooxidant status in Fe preconditioning against ischemia (1 h)-reperfusion (20 h) induced liver injury was assessed using N-acetylcysteine (NAC) (1 g/kg) before Fe (50 mg/kg), given to male Sprague Dawley rats on alternate days during 10 days. IR significantly increased serum aspartate transaminase (AST) and alanine transaminase (ALT) levels, with drastic changes i...

2017
Shigekazu Ukawa Emiko Okada Koshi Nakamura Makoto Hirata Akiko Nagai Koichi Matsuda Zentaro Yamagata Yoichiro Kamatani Toshiharu Ninomiya Yutaka Kiyohara Kaori Muto Michiaki Kubo Yusuke Nakamura Hiromasa Harada Kiyoshi Kaneko Shuichi Matsumoto Masaki Shiono Shiro Minami Hiroshi Yoshida Nobuhiko Taniai Sumio Watanabe Noriko Fujiwara Atsuyuki Yamataka Satoshi Asai Mitsuhiko Moriyama Yasuo Takahashi Tomoaki Fujioka Wataru Obara Seijiro Mori Hideki Ito Satoshi Nagayama Yoshio Miki Akihide Masumoto Akira Yamada Yasuko Nishizawa Ken Kodama Shigeyuki Naka Yoshihiro Endo Yukihiro Koretsune Eiji Mita Kozo Morimoto Akiko Tamakoshi

BACKGROUND Liver cancer is the fifth cause of cancer-related deaths in Japan. The BioBank Japan (BBJ) project included 200,000 patients with 47 diseases and samples; their clinical information can be used for further studies. METHODS Patients diagnosed with liver cancer (n = 1733; 1316 men, 417 women) were included. Histology, patient characteristics, clinical characteristics, and causes of d...

Journal: :PloS one 2015
Xingmu Liu Chao He Tao Huang Jiang Gu

BACKGROUND Sleeve anastomosis is the most common technique used to rearterialize orthotopic liver transplants (OLT). However, this technique has a number of disadvantages, including difficulty of performance of the technique visually unaided. We herein describe a novel rearterialized OLT model in the rat. MATERIALS AND METHODS Forty-six male Sprague Dawley rats (300-400 g) were used as donors...

2008
Chen Wang You Qing Xu

Diphenyl dimethyl bicarboxylate (DDB) has been used in some countries as hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis, chemical or drug induced hepatic damage. Its early confirmed efficacy is to normalize elevated blood alanine aminotransferase (ALT) from different etiologies, however, it can rarely affect the rest hepatic enzymes. In addition, t...

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