Meningiomas are usually slow growing neoplasms that follow a benign clinical course. However, atypical and anaplastic meningiomas can show more aggressive behaviour have the potential to metastasise. The most common sites for metastases lung, spine, soft tissue, liver bone. Bone exceedingly rare. We report case of 70-year-old man with previous history recurrent meningioma (WHO grade III) pathol...

Abstract Objectives The study aims to develop a stable malnourished experimental mice model resembling the human population for future studies. Materials and Methodology At weaning, female BALB/c are separated into two groups: one receiving low protein diet (LPD, 10% protein) other commercially available normal pellet (ND, 18% protein). Model development stability were assessed using body mass ...

Mycotoxins are natural food and feed contaminants produced by several molds. The primary mode of exposure in humans animals is through mixtures. Aflatoxin B1 (AFB1) sterigmatocystin (STER) structurally related mycotoxins that share the same biosynthetic route. Few vivo genotoxicity assays have been performed with STER. In present study, Wistar rats were dosed orally STER (20 mg/kg b.w.), AFB1 (...

Deposition of arsenic in mice through groundwater is well documented but little is known about the histological changes of organs by the metalloid. Present study was designed to evaluate arsenic-induced histological alterations in kidney, liver, thoracic artery and brain of mice which are not well documented yet. Swiss albino male mice were divided into 2 groups and treated as follows: Group 1:...

Purpose To report a case of primary hepatoid adenocarcinoma of the orbit. Observations An adult patient was referred for evaluation of an orbital mass. Histopathology of the orbital biopsy indicated a carcinoma with hepatoid features. Laboratory studies revealed normal liver function tests, elevated serum alpha-fetoprotein, and whole-body positron emission tomography/computed tomography scan ...

BACKGROUND Nitrofurantoin is a commonly prescribed urinary antiseptic. Hepatic injury has been associated with its use. OBJECTIVES To present three patients in whom long-term exposure to the drug resulted in chronic active hepatitis; and to review the epidemiology, clinical immunology, histopathology, pathogenetic features and treatment of previously reported cases. RESULTS Withdrawing nitr...

Toxocariasis is an extensive helminthic infection that leads to visceral larva migrans in humans. A 2.5-year-old girl referred for abdominal mass. She had history of pharyngitis for two weeks. There were no other symptoms. Abdominal examination revealed an irregular solid mass in right lower quadrant (RLQ). Abdominal ultrasonography revealed an echohetrogenic large mass in RLQ, liver, and retro...

S3 Fig. Histopathology studies of tissue organs from a mouse injected with nanovaccine immunisations; A) Three weeks post the final immunisation, organs fixed in formalin were harvested from two mice for each treatment group and embedded in paraffin, sections were stained with hematoxylin and eosin stain. i) Heart, ii) Injection sites, iii) Kidney, iv) Liver. B) Six months post the final immuni...