The quantification of phospholipid hydroperoxides in biological tissues is important in order to know the degree of peroxidative damage of membrane lipids. For this purpose, optimal conditions for the chemiluminescent simultaneous assay of phosphatidylcholine hydroperoxide (PCOOH) and phosphatidylethanolamine hydroperoxide (PEOOH) in rat liver and brain were determined. A chemiluminescence dete...

this study investigated the cytochemical responses in hediste diversicolor exposed to the environmental concentrations of cadmium (1µm cd), copper (1µm cu) and to their equimolar mixture for 48h. lysosomal membrane stability (lms), neutral lipids (nl) level, lipofuscin (lf) content and ca2+-atpase activity were determined as early subcellular biomarkers of toxicity. the biomarker battery pointe...

pythium irregulare oomycetes adapts with environmental changes including crude oil concentration by changing the composition of lipids in the cytoplasmic membrane and providing the required characteristics for adaptation in improper and stressful environmental situations. it was found that cultivation of pythium irregulare lx oomycetes in the nutrient media with different concentrations of crud...

The effects of incorporating cyanoglucoside extracts from yam or dasheen into the diet of streptozotocin-induced diabetic Wistar rats were studied for four weeks. Intestinal lipase activity, and plasma glucose and lipid levels were determined. Also, liver total lipids, activities of ATP citrate lyase, pyruvate kinase and 6-phosphogluconate dehydrogenase were assessed. Dasheen extract significan...

UNLABELLED In humans, antidiabetics thiazolidinediones (TZDs) upregulate stearoyl-CoA desaturase 1 (SCD1) gene in adipose tissue and increase plasma levels of SCD1 product palmitoleate, known to enhance muscle insulin sensitivity. Involvement of other tissues in the beneficial effects of TZDs on plasma lipid profile is unclear. In our previous study in mice, in which lipogenesis was suppressed ...

RATIONALE The eco-physiological mechanisms that govern the incorporation and routing of macronutrients from dietary sources into consumer tissues determine the efficacy of stable isotope analysis (SIA) for studying animal foraging ecology. We document how changes in the relative amounts of dietary proteins and lipids affect the metabolic routing of these macronutrients and the consequent effect...

It has previously been shown that when the molecular species specificity of rat liver Golgi CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase was determined, using as the substrate lactosylceramide (LacCer) incorporated into liposomes prepared with rat liver Golgi lipids, the enzyme showed a pronounced variation in activity towards the various molecular species of LacCer (J. ...

BACKGROUND In recent years, the number of people with metabolic syndrome has continued to rise because of changing eating habits, and accompanying hepatic steatosis patients have also increased. This study examined the effect of guava leaf extract on liver fat accumulation using SHRSP.Z-Leprfa/IzmDmcr rats (SHRSP/ZF), which are a metabolic syndrome model animal. METHOD Seven-week-old male SHR...

The toxicity of fluoride (F) to 16-cm long fresh water male catfish (Clarias batrachus, Linn.) was evaluated after their exposure to two sub-lethal concentrations of NaF (35 mg F ion/L and 70 mg F ion/L) for 90 days. Changes in biochemical parameters in muscle, liver, and testis tissues were recorded. Significant depletion of total protein and lipids in these tissues occurred at both the lower ...

Ethanol introduced into the organism undergoes rapid metabolism to acetaldehyde and then to acetic acid. The process is accompanied by formation of reactive oxygen species (ROS), which damage mainly lipids of membrane cells. The effects of ROS can be neutralized by administering preparations with antioxidant properties. The natural preparations of this kind are teas.This paper reports data on t...