Hepatitis C infection is one of the most common causes of chronic end-stage liver disease, with its sequelae decompensated liver cirrhosis and hepatocellular carcinoma. Both are currently the most important indications for liver transplantation [1]. Unfortunately, almost all patients with detectable HCV RNA at the time of transplantation will have recurrent hepatitis C in their graft [2]. Altho...

Currently, liver transplantation has reached a level of maturity where it is considered an effective treatment for end-stage disease and can significantly prolong the survival time patients. However, acute chronic rejection remain major obstacles to its efficacy. Although long-term use immunosuppressants prevent rejection, associated with serious side effects significant economic burden Therefo...

74% of the survivors of liver transplantation for alcoholic liver disease are able to work and contribute to society as a result of having had the transplant procedure. Probably the most surprising statistic concerning liver transplantation for alcoholic liver disease is the finding that 89.5% of the transplant survivors have remained alcoholabstinent. 12 Of those that have resumed drinking, th...

Post-transplant malignancy is the major cause of later death of recipients after liver transplantation. Tumor recurrence after liver transplantation for patients with hepatocellular carcinoma in the end stage of cirrhosis has been frequently encountered. However, de novo hepatocellular carcinoma originating from the liver allograft has only rarely been reported. Here we reported a case of de no...

Correction Contact me if this article is corrected. Citations Contact me when this article is cited. Topic collections Contact me when new articles are published in these topic areas. Intervention Other; Gastroenterology; Liver/ Biliary Tract/ Pancreatic Diseases; Cardiovascular Transplantation; Kidney Transplantation; Liver Transplantation; Transplantation, Cardiothoracic Surgery; Endocrine Su...

BACKGROUND AND AIM Liver transplantation is a potential cure for liver damage from Wilson's disease but the course of neuropsychiatric manifestations after transplantation remains undetermined. MATERIAL AND METHODS In this study, data on all patients who'd received a liver transplant for Wilson's disease at the Shiraz Organ Transplantation Center between December 2000 and March 2014 were revi...

The ultimate therapeutic step in the treatment of hepatic disease is the provision of a new liver with or without removal of the affected native organ. As of the writing of this manuscript, nearly 2000 liver transplants have been performed in the United States alone. Probably another 1000 have been performed in other parts of the world. Two approaches to liver transplantation have been utilized...

Liver transplantation is now the preferred treatment for many diseases leading to end-stage liver disease. Transplantation for cancer has been disappointing and there is a significant recurrence rate after transplantation in hepatitis B-virus carriers. Additional strategies will have to be developed if we are to improve the results of transplantation for these patients. The role of immunologica...

1 Starzl TE, Groth CG, Brettschneider L, Penn I, Fulginiti VA, Moon JB, et al. Orthotopic homotransplantation of the human liver. Ann Surg 1%8;168: 392-415. 2 National Institutes of Health Consensus Development. Conference statement: liver transplantation-June 20-23. Hepatology 1984;4(suppl): 107-10. 3 Starzl TE, Koep LJ, Schroter GPJ, Halgrimson CG, Porter KA, Weil R. Liver replacement for ped...

Background: Alcoholic liver cirrhosis is a common indication for liver transplantation. Recurrence of alcohol use was retrospectively analyzed after liver transplantation. Methods: From X/1995 to II/2002, 42 out of 246 patients underwent liver transplantation for alcoholic liver cirrhosis. We administered a questionnaire to all patients surviving at least 1 year post liver transplantation for a...