The backpack is one of the several forms of manual load carriage that provides versatility and is often used by bikers, backpackers and soldiers, as well as school students. However, musculoskeletal problems associated with backpack use have become an increasing concern with school children . The combined effects of heavy load, position of the load on the body, size and shape of the load, load ...

The problem concerning the nature and the function of the dead space is of basic importance for the full comprehension of the respiratory physiology and pathophysiology. To study the effect of an imposed external dead space on the optimal respiratory control system, we simulated the optimal neuro-muscular drive and respiratory signals, including instantaneous airflow and lung volume profiles, w...

Vancomycin hydrochloride (VCM) is a glycopeptides antibiotic. We intend to optimize preparation condition of VCM nanoparticles. Nanoparticles have high bioavailability and oral absorbable fraction. After drug to polymer ratio optimization, loading efficiency, production yield and particle size were measured by changing the organic phase volume, aqueous phase volume and emulsifier concentration ...

Timo Ojasto 2007. The effect of different accentuated eccentric load levels in eccentricconcentric loading contractions on acute neuromuscular, growth hormone and blood lactate responses during a hypertrophic protocol. Science of Sport Coaching and Fitness Testing, Department of Biology of Physical Activity, University of Jyväskylä. 92 pp. When accentuated load is applied during the eccentric (...

In recent years, encapsulation of drugs and antigens in hydrogels, specifically in calcium alginate particles, is an interesting and practical technique that was developed widespread. It is well known that alginate solution, under proper conditions, can form suitable nanoparticles as a promising carrier system, for vaccine delivery. The aim of this study was to synthesis alginate nanoparticles ...

The mechanics of the formation and propagation of ridges on compressed stiff film/compliant substrate systems is studied theoretically and experimentally. Ridges form on bilayer systems where the elastomeric substrate is subject to a significant pre-stretch prior to attachment of the film. When the bilayer is then subject to increasing overall compressive strain, sinusoidal wrinkles first form ...

Metabolic syndrome is a highly predisposing condition for cardiovascular disease and could be a cause of excess salt-induced organ damage. Recently, several investigators have demonstrated that salt loading causes left ventricular diastolic dysfunction associated with increased oxidative stress and mineralocorticoid receptor activation. We, therefore, investigated whether excess salt induces ca...

Introduction The articular cartilage in the knee joint provides load-bearing function along with adjacent meniscus and anterior/posterior cruciate ligaments, and injury of the meniscus, cruciate ligaments and articular cartilage may result in failure in responding to normal load-bearing. Previous clinical studies showed that 80% or more patients with injury of anterior cruciate ligaments result...

We report laboratory experiments to investigate the role of gas desorption, stress level and loading rate on the mechanical behavior of methane infiltrated coal. Two suites of experiments are carried out. The first suite of experiments is conducted on coal (Lower Kittanning seam, West Virginia) at a confining stress of 2 MPa and methane pore pressures in the fracture of 1 MPa to examine the rol...

This study was to investigate the influence of composite resins with different elastic modulus, cavity modification and occlusal loading condition on the stress distribution of restored notch-shaped noncarious cervical lesion using 3-dimensional (3D) finite element (FE) analysis. The extracted maxillary second premolar was scanned serially with Micro-CT. The 3D images were processed by 3D-DOCTO...