BACKGROUND Although femoral nerve block provides satisfactory analgesia after total knee arthroplasty (TKA), residual posterior knee pain may decrease patient satisfaction. We conducted a randomized controlled trial to clarify the efficacy of the sciatic nerve block (SNB) and local infiltration of analgesia with steroid (LIA) regarding postoperative analgesia after TKA, when administrated in ad...

BACKGROUND To manage intractable cancer pain, an alternative to systemic analgesics is neuraxial analgesia. In long-term treatment, intrathecal administration could provide a more satisfactory pain relief with lower doses of analgesics and fewer side-effects than that of epidural administration. However, implantable drug delivery systems using intrathecal pumps in Korea are very expensive. Cons...

BACKGROUND Perineural administration of thiamine, via axonal flow, could strenghthen synthesis of ACh in the dorsal horn inhibitory interneurons, thus potentiating analgesia. The purpose of the present retrospective analysis is therefore to investigate whether adding perineurally 2 mg/Kg of thiamine to 0.75% levobupivacaine in patients undergoing middle interscalene block may prolong the durati...

Objectives: Alpha-2-receptor agonist has been used as an additive to local anaesthetics for various regional anaesthetic techniques. We compared clonidine and dexmedetomidine as an adjuvant to local anaesthetic agent in ultrasound guided axillary brachial plexus block with respect to hemodynamic parameters, onset and duration of sensory, motor block and duration of analgesia. Methods: Ultrasoun...

Extradural co-administration of opioids and local anaesthetics is a popular method for control of pain [3, 5, 18]. Spinal and epidural administration of opioids produce a profound and long lasting segmental analgesia, which is not associated with sensory, sympathetic, or motor blockade [2, 4]. The side effects of epidural opioids in men are dose-dependent and may include pruritus, nausea, respi...

AIM Vitrectomies are performed either under general anesthesia (GA), local anesthesia (LA), or a combination of both. Postoperative pain is expected to be less in patients with LA because of prolonged action of the local anaesthetic. Pre-emptive analgesia is based on the idea that analgesia initiated before a nociceptive event will be more effective than analgesia commenced afterwards. The auth...

Introduction: Monitored Anesthesia Care (MAC) is proposed to be a suitable technique for middle ear surgery. Aim: In present study we compared the efficiency of dexmedetomidine and propofol as an adjunct to local anesthesia for in producing analgesia, sedation, variation in respiratory and hemodynamic responses, along with patients and surgeons satisfaction. Materials and Methods: Fifty patient...

PURPOSE OF REVIEW Although postoperative analgesia in infants and children should be an integral part of the perioperative management, undertreatment of pain is not rare in clinical practice and may influence outcome and long term behaviour. Therefore, this review summarizes results of recent papers and discusses actual trends and future perspectives concerning postoperative pharmacologic pain ...