نتایج جستجو برای: locally advanced breast cancer

تعداد نتایج: 1240549  

2011
Seeyoun Lee Seok Won Kim Seok-Ki Kim Keun Seok Lee Eun A Kim Youngmee Kwon Kyung Hwan Shin Han-Sung Kang Jungsil Ro Eun Sook Lee

PURPOSE Preoperative chemotherapy has been used to increase the rate of breast conserving surgery (BCS) in Caucasian women. However, whether it would also increase the rate of BCS in Korean women has not been verified. The aim of this study was to determine the effectiveness of preoperative chemotherapy to make BCS possible in Korean women who have locally advanced cancer without any increase o...

2017
Robert W Gao Shane Edlund Jianling Yuan

Although advances in screening mammography have dramatically improved the early detection of breast cancer, a subset of breast cancer cases still present as locally advanced disease. Some of these patients develop fungating lesions, which are difficult to manage and can have a severe impact on the quality of life. Palliative treatment options include surgery, intra-arterial chemotherapy, and ra...

2016

[This corrects the article DOI: 10.1097/GOX.0000000000000598.].

2013
Giuseppe Curigliano Carmen Criscitiello Angela Esposito Luca Fumagalli Lucia Gelao Marzia Locatelli Ida Minchella Aron Goldhirsch

1359-6349/$ see front matter Copyright 2013 ECCO – the European CanCer Organisation. All rights reserved. http://dx.doi.org/10.1016/j.ejcsup.2013.07.052 * Corresponding author: Tel.: +39 02 57489788; fax: +39 02 57489581. E-mail address: [email protected] (G. Curigliano). Giuseppe Curigliano *, Carmen Criscitiello, Angela Esposito, Luca Fumagalli, Lucia Gelao, Marzia Locatelli, Ida Min...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Ellen L Jones Leonard R Prosnitz Mark W Dewhirst P Kelly Marcom Patricia H Hardenbergh Lawrence B Marks David M Brizel Zeljko Vujaskovic

PURPOSE The purpose of this research was to evaluate toxicity, response, and changes in oxygenation (pO(2)) in patients with locally advanced breast cancer (LABC) treated with concurrent taxol, hyperthermia (HT), and radiation therapy (RT) followed by mastectomy. EXPERIMENTAL DESIGN Eighteen patients with LABC were enrolled from October 1995 through February 1999. Treatment consisted of taxol...

2014
Icro Meattini Sara Cecchini Vanessa Di Cataldo Calogero Saieva Giulio Francolini Vieri Scotti Pierluigi Bonomo Monica Mangoni Daniela Greto Jacopo Nori Lorenzo Orzalesi Donato Casella Roberta Simoncini Massimiliano Fambrini Simonetta Bianchi Lorenzo Livi

Neoadjuvant chemotherapy (NAC) is widely used in locally advanced breast cancer (BC) treatment. The role of postmastectomy radiotherapy (PMRT) after NAC is strongly debated. The aim of our analysis was to identify major prognostic factors in a single-center series, with emphasis on PMRT. From 1997 to 2011, 170 patients were treated with NAC and mastectomy at our center; 98 cases (57.6%) underwe...

2015
ATSUKO YAMADA SHINJI OSADA TOSHIYUKI TANAHASHI SATOSHI MATSUI YOSHIYUKI SASAKI YOSHIHIRO TANAKA NAOKI OKUMURA NOBUHISA MATSUHASHI TAKAO TAKAHASHI KAZUYA YAMAGUCHI KAZUHIRO YOSHIDA

To evaluate a novel therapy for triple-negative breast cancer (TNBC), the biological responses to vitamin K3 (VK3) should be considered with the understanding of the features of breast cancer. In human breast cancer cell lines, the effects of VK3 on cell growth inhibition and the cellular signaling pathway were determined by MTT assay and western blotting. In the in vivo study, a subcutaneous t...

Journal: :Acta medica portuguesa 2013
Marisa Padilha Sara Gonçalves Carlos Fardilha Gilberto Melo Cristina Miranda Paula Alves

INTRODUCTION Breast cancer is a major cause of death in our country. The Department of Radiation Oncology of Portuguese Institute of Oncology in Coimbra are using a scheme of hypofraccionation called "Flash" as a treatment option for elderly patients or low performance status, with locally advanced breast cancer, or with stage IIb or IV, as a neoadjuvante or palliative aim. OBJECTIVES Evaluat...

2017
M. N. Duma C. Heinrich C. Schönknecht B. Chizzali M. Mayinger M. Devecka S. Kampfer S. E. Combs

PURPOSE We report our experience of using helical tomotherapy (HT) to treat large and irregular shaped loco-regional advanced breast cancer target volumes embracing various organs at risk. PATIENTS AND METHODS We retrospectively analyzed 26 patients treated for very large, irregular shaped breast cancers. Patients were treated either with the intent to achieve local control in a primary setti...

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