This study tested the null hypothesis that antihistamine-containing syrup does not change salivary metabolites in vitro and vivo. For experiments, saliva from 10 volunteers was mixed with a or pill suspension of loratadine (1 mg/ml Claritin®, Schering-Plough, Rio de Janeiro, Brazil). vivo experiment, performed mouth rinse mL antihistamine (Claritin®; Brazil) for 20 seconds then discarded water....