نتایج جستجو برای: low dose effects
تعداد نتایج: 2762041 فیلتر نتایج به سال:
BACKGROUND Heart attack is the most common cause of line-of-duty death in the fire service. Daily aspirin therapy is a preventative measure used to reduce the morbidity of heart attacks but may decrease the ability to dissipate heat by reducing skin blood flow. METHODS In this double-blind, placebo-controlled, crossover study, firefighters were randomized to receive 14 days of therapy (81-mg ...
This project assessed the effects of repeated low-dose exposure of guinea pigs to the organophosphorus nerve agent sarin. Animals were injected once a day, 5 days per week (Monday-Friday), for 2 weeks with fractions (0.3x, 0.4x, 0.5x, or 0.6x) of the established LD(50) dose of sarin (42 microg/kg, s.c.). The animals were assessed for changes in body weight, red blood cell (RBC) acetylcholineste...
Objective(s): This study aimed to show the effects of thymoquinone, which is known for its antioxidant, anti-inflammatory, and renal protective effects in contrast-induced nephropathy.Materials and Methods: This is an experimental study in rats. 7 groups were included within the scope of our study: sham-vehicle (n=3), premedication-contr...
OBJECTIVES This study aimed to compare the QTc interval between low and high dose methadone groups and evaluate the pattern of QTc variation. METHODS This is a prospective cohort study conducted from December 2010 till August 2011 at Malaysian University of Science's Hospital. Forty six subjects, grouped in high dose (>80mg) and low dose (<80mg) oral methadone, were followed-up at 4-weekly fo...
This phase 1b/2a, randomized, double-blind, placebo-controlled, dose-escalation trial tested low-dose subcutaneous aldesleukin (recombinant IL-2) in patients with ischemic heart disease. Low-dose IL-2 expanded Tregs, without adverse events of major concern. Single-cell RNA-sequencing circulating immune cells was used to provide mechanistic assessment the treatment’s effects.
aspirin is an anti-inflammatory drug, peroxyl radical scavenger, and antioxidant agent that inhibits phospholipases, nitric oxide synthetases, and cyclooxygenase enzymes. the existing literature contains no studies on the effects of various doses of aspirin on spinal cord injury (sci). therefore, we sought to investigate the putative effects of aspirin on experimental sci. the weight-drop injur...
Introduction: Shivering is one of the complications of spinal anesthesia. There are various methods to control this shivering. In this research we opted to study the effects of two different combination doses of ketamine and midazolam on the prevention of shivering after spinal anesthesia. Material and methods: Methods:The study was a double-blind clinical trial performed on 120 patients who w...
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