Extranodal marginal zone lymphoma is a low-grade B cell lymphoma that presents with an indolent clinicopathologic nature. Although this tumor can occur in various sites, including the gastrointestinal tract and lungs, it develops and spreads extremely rarely along the trachea and central airway. We report a case of extranodal lymphoma of mucosa-associated lymphoid tissue with tracheobronchial i...

BACKGROUND AND OBJECTIVES In follicular lymphoma histological grading is used to predict clinical behavior and to stratify patients for treatment. However, the reproducibility of histological grading is poor and the clinical significance of the difference between grade 1 and grade 2 follicular lymphoma is unclear. Data on proliferation characteristics with respect to prognosis in follicular lym...

autoimmune hemolytic anemia (aiha) is characterized by shortening of red blood cell (rbc) survival and the presence of autoantibodies directed against autologous rbcs. approximately 20% of autoimmune hemolytic anemia cases are associated with cold-reactive antibody. about half of patients with aiha have no underlying associated disease; these cases are termed primary or idiopathic. secondary ca...

BACKGROUND Data regarding childhood and adolescent non Hodgkin lymphomas in Iran are limited. The aim of this study was to assess the epidemiological and histomorphological features and survival of affected patients in our center. MATERIALS AND METHODS The clinicopathologic features and outcome of 44 children and adolescents with non Hodgkin lymphoma diagnosed during 2004-2012, were investiga...

We have shown previously that cancer/testis (CT) antigen, CT45, is expressed in various epithelial cancers at a frequency of <5% to approximately 35%. In this study, the protein expression of CT45 was examined in non-Hodgkin B-cell lymphomas and classical Hodgkin lymphoma by immunohistochemical analysis. Serological response to CT45 was also evaluated by ELISA using CT45 recombinant protein and...

Summary AL amyloidosis (AL) and monoclonal gammopathy of renal significance (MGRS) are both paraprotein-associated diseases. Both entities based on a paraprotein produced by clonal plasma-cell population like in undetermined (MGUS) or B-cell low grade lymphoma. Per definition MGUS low-grade lymphoma do not require treatment. But rare cases the M‑gradient acts as “toxic” protein inducing severe ...

OBJECTIVE To determine survival rates of patients with lymphoma in South Australia. DESIGN AND SETTING De-identified data from the SA Cancer Registry on all patients with lymphoma were analysed, as well as the subgroup treated at the Royal Adelaide Hospital (RAH). For non-Hodgkin lymphoma (NHL), we used the International Working Formulation (IWF) grading. SA and RAH data on survival rates wer...

the blood brain-barrier, trimethoprim/sulphamethoxazole (160/800 mg every 8 hours) and amikacin (500 mg every 12 hours). The patient’s clinical condition slowly deteriorated and the patient died 73 days after the start of the antibiotic treatment. Post-mortem examination confirmed the diagnosis of CNS and pulmonary nocardiosis. Infection remains a major cause of significant morbidity and mortal...

To clarify the clinicopathological findings of B-cell lymphoma associated with Sjögren’s syndrome (SJS) among Japanese Patients, 15 individuals with this disease were studied. The patients, 14 females and one male, ranged in age from 41 to 73 years with a median age of 56 years. These lymphomas arose not only in the salivary gland (n=4) but also in other mucosal extranodal sites (n=5). Histolog...