We determined the effects of bilateral microinjection of muscimol and excitatory amino acid receptor antagonists into the medullary lateral tegmental field (LTF) on changes in sympathetic nerve discharge (SND), mean arterial pressure (MAP), and phrenic nerve activity (PNA; artificially ventilated cats) or intratracheal pressure (spontaneously breathing cats) elicited by right atrial administrat...

UNLABELLED Treatment of oropharyngeal squamous cell carcinoma with chemoradiotherapy can now accomplish excellent locoregional disease control, but patient overall survival (OS) remains limited by development of distant metastases (DM). We investigated the prognostic value of staging (18)F-FDG PET/CT, beyond clinical risk factors, for predicting DM and OS in 176 patients after definitive chemor...

Two forms of lactoferrin, an intact lactoferrin and a "nicked" but apparently intact (i.e., 78-kDa) form, have been isolated from the urine of preterm infants fed human milk. These two forms of lactoferrin, demonstrated to be entirely of maternal origin, were copurified using affinity columns of immobilized single-stranded DNA-agarose. The relative concentrations of the intact lactoferrin and t...

A new method has been developed that allows spatially resolved adsorption of lactoferrin on a surface, by means of specific non-covalent interaction between the native protein and a patterned self-assembled monolayer of an iron-containing terpyridine complex.

The aim of this study was to determine the therapeutic efficacy of lactoferrin (Lf) on dextran sulphate sodium (DSS)‑induced experimental colitis in BALB/c mice. Eighty BALB/c mice were randomly divided into 4 groups; the normal, model, apo‑Lf and holo‑Lf groups. Fecal character, fecal occult blood, hematochezia and disease activity index (DAI) were recorded daily. The length of the colon was m...

PURPOSE To identify the novel gene signatures and molecular markers of nasopharyngeal carcinoma (NPC) by integrated bioinformatics analysis of multiple gene expression profiling datasets. EXPERIMENTAL DESIGN Seven published gene expression profiling studies and one of our unpublished works were reanalyzed to identify the common significantly dysregulated (CSD) genes in NPC. Overrepresentation...

Introduction Chronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by infiltration plasma cells in endometrial stroma. CD138 immunohistochemistry considered to improve CE diagnosis rate. Methods Using number CD138-positive equal or greater than five as diagnostic criterion for CE, we identified 24 and 33 non-CE cases among women with infertility. We c...

The strain WBS, an anaerobic, psychro- and halotolerant bacterium belonging to the genus Fusibacter, was isolated from littoral bottom sediments of White Sea, Arctic, Russia. Fusibacter bizertensis WBS grew at temperatures between 8 32 °C (optimum growth 18–20 °C), pH 5.2 8.3 7.2), NaCl concentrations 0 70 g L−1 L−1). It reduced sulfate, thiosulfate, elemental sulfur into sulfide, and, probably...

Novel and traditional eggshell quality measurements were made from up to 2000 commercial pedigree hens for a candidate gene association analysis with organic eggshell matrix genes: ovocleidin-116, osteopontin (SPP1), ovocalyxin-32 (RARRES1), ovotransferrin (LTF), ovalbumin and ovocalyxin-36, as well as key genes in the maintenance and function of the shell gland [estrogen receptor (ESR1) and ca...