Lung injury is the term used to describe the pulmonary response to a broad range of injuries occurring either directly to the lung or as the consequence of injury or inflammation at other sites in the body. Acute respiratory distress syndrome (ARDS) represents the more severe end of the spectrum of this condition in which there are widespread inflammatory changes throughout the lung, usually ac...

there are few reported cases of endobronchial metastasis of pheochromocytoma literature. we present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. computed tomography showed a lobulated soft tissue mass, measuring, 38×27 mm, at the perivascular space of anterior mediastinum. the resected specimen, showed lobulated tumo...

conclusions physicians should be aware of this rare site of metastasis. early diagnosis is of paramount importance in order to effectively prevent the significant morbidity this condition can cause if left untreated. introduction small cell carcinoma constitutes the most aggressive type of lung cancer, with the greatest propensity for early disseminated disease. although commonly neglected due ...

Hemoglobin-vesicles (HbV), encapsulating highly concentrated human hemoglobin in liposomes, were developed as a substitute for red blood cells (RBC) and their safety and efficacy in transfusion therapy has been confirmed in previous studies. Although HbV suspensions are structurally and physicochemically stabile for least 1-year at room temperature, based on in vitro experiments, the issue of w...

According to statistics, chest injuries rank third in prevalence and are characterized by high mortality, which is 35 – 45%. This article presents a patient diagnosed treated for bilateral pulmonary contusion with post-traumatic pneumonitis after combined mine-explosive injury. Purpose. Of particular interest the clinician understanding of lung injury from standpoint interpretation diagnosis, m...

Use of normothermic ex vivo lung perfusion (EVLP) was adopted in clinical practice to assess the quality marginal donor lungs. Subnormothermic temperatures are use among other solid organs improve biochemical, and immunological parameters. In a rat EVLP model donation after circulatory death (DCD) donors, we tested effect four subnormothermic that could further organ preservation. Warm ischemic...

Severe acute respiratory distress syndrome (ARDS) presents typically with an initializing event, followed by the need for mechanical ventilation. Most animal models of ALI are limited by the fact that they focus on a singular cause of acute lung injury (ALI) and therefore fail to mimic the complex, multifactorial pathobiology of ARDS. To better capture this scenario, we provide a comprehensive ...

BACKGROUND AND OBJECTIVES Patients who need to stay under endotracheal intubation for long periods or when undergoing general anesthesia may develop tracheal lumen injuries due to pressure from distal cuff. In some cases, these injuries may evolve to stenosis or, occasionally, necrosis. The objective of this study was to present a modified endotracheal tube (METT) in which the cuff pressure is ...

Traumatic chest injury with complete tracheo- bronchial disruption is uncommon and occurs in approximately 1% of motor vehicle accidents (MVA) (1,2). Such injuries carry a high mortality and patients rarely survive transfer to hospital. A high index of suspicion facilitates early diagnosis. Early operative intervention is vital for survival. We describe a rare case of traumatic complete disrupt...

Mediastinal radiation is commonly used to treat Hodgkin's and non-Hodgkin's lymphoma, lung and breast cancer. Cardiac complications after radiation therapy are well described, although rare. A large spectrum of injuries can occur, causing long term morbidity among survivors. We describe a case of post-actinic ascending aortic wall thickening that prevented saphenous vein proximal anastomosis an...