introduction: the complex geometry of breast and also lung and heart inhomogeneities near the planning target volume (ptv) result in perturbations in dose distribution. this problem can result in overdosage or underdosage in the match region of the three treatment fields. the purpose of this study is to create a homogeneous dose distribution in the match region between the supraclavicular and t...

Physiologically based pharmacokinetic (PBPK) modeling involves mathematically describing the complex interplay of the critical physicochemical and biological determinants involved in the disposition of chemicals. In this approach, the body is divided into a number of biologically relevant tissue compartments, arranged in an anatomically accurate manner, and defined with appropriate physiologica...

Organized by Working Group 6 “Computational Dosimetry” of the European Radiation Dosimetry (EURADOS), a group intercomparison exercises was conducted in which participants were asked to solve predefined problems computational dosimetry. The results these comparisons published series articles this virtual special issue Measurements. This paper reviews experience gained from various and highlight...

INTRODUCTION The current practice of internal dosimetry for occupational workers handling actinides, in particular Pu/Am, involves monitoring of intakes. This, in turn, requires assessments of internal actinide contamination of the relevant body organs. Such assessments are needed: a) more often and almost on a routine basis for lungs for the recent as well as old exposures; b) comparatively le...

many studies have been performed for treatment or prevention of pulmonary fibrosis. however, no effective treatment has been found yet. the aim of this study was to investigate the effect of grape seed extract on bleomycin-induced lung fibrosis in rat. hydroalcoholic extract of grape seed (vitis vinifera) was prepared using maceration method. nmri rats weighing 250-300 g were given single intra...

PURPOSE To analyze the seed loss and displacement and their dosimetric impact in prostate low-dose-rate (LDR) brachytherapy while utilizing the combination of loose and stranded seeds. MATERIAL AND METHODS Two hundred and seventeen prostate cancer patients have been treated with LDR brachytherapy. Loose seeds were implanted in the prostate center and stranded seeds in the periphery of the gla...

PURPOSE Perform a retrospective dosimetry study of total body irradiation (TBI) on leukemia and bone marrow transplant patients. METHODS The in vivo dosimetry data of 129 patients treated with TBI between 2008 and 2011 were retrieved from the database and analyzed. These patients were mostly treated with the regime of a single fraction or 6 fractions with some exceptions of 8-fraction or 2-fr...