نتایج جستجو برای: lymphoblastoid cell lines
تعداد نتایج: 1795243 فیلتر نتایج به سال:
2-Chloro-2'-deoxyadenosine, (CldAdo) resistance was developed in the W1L2 human B lymphoblastoid (resistance factor, 160) and L1210 murine leukemia (resistance factor, 605) cell lines by continuous exposure to CldAdo. Cross-resistance studies showed that while the variant lines generally retained sensitivities to 9-beta-D-arabinofuranosyladenine (in the presence of 2'-deoxycoformycin), hydroxyu...
EBV-positive nasopharyngeal carcinoma and Hodgkin, T, and natural killer (NK) lymphomas express EBNA-1 and the latent membrane proteins (LMP1-2; type II latency). In contrast to type III EBV-transformed lymphoblastoid cell lines, in these cells the LMPs are expressed in the absence of EBNA-2. We have previously reported that exposure to CD40 ligand and IL-4 could induce LMP-1 in an in vitro EBV...
ABCB1 (adenosine triphosphate-binding cassette transporter B1) mediates cellular elimination of many chemotherapeutic agents including paclitaxel, which is commonly used to treat ovarian cancer. A significant association between common single nucleotide polymorphisms (SNPs) in ABCB1 and progression-free survival has been reported in patients with ovarian cancer. Variable paclitaxel clearance du...
To determine the susceptibility of rabbits to experimental infection with human T-cell lymphotropic virus type4 (HTLV11). four separate groups of four weanling rabbits each were inoculated intravenously with lethally irradiated HTLV-IIinfected human cell lines Mo-T (HTLV-11,-infected T cells), WIL-NRA (an Epstein-Barr virus [EBVI-transformed B-lymphoblastoid cell line infected with HTLV-I,), 72...
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