The gastrointestinal (GI) tract is a common site of presentation of extranodal lymphomas, although primary GI lymphomas account for only 5% to 10% of primary GI neoplasms. The majority of cases occur in the stomach; only approximately 10% occur in the colorectum. Diffuse large B-cell lymphoma is the most common type of GI tract lymphoma [1]. An asymptomatic 55-year-old man was referred for endo...

BACKGROUND AND AIMS Castleman's disease is a rare disorder situated at the boundary between reactive and neoplastic conditions. The pathogenesis is a subject of debate and the limited number of cases renders the study of the disease difficult. In our paper we present a series of six cases of Castleman disease with emphasis on the clinical presentation, pathology examination and the use of immun...

Cutaneous lymphoid hyperplasia (CLH) can be idiopathic or secondary to external stimuli, and is considered rare in tattoos. The infiltrate can be predominantly of B or T-cells, the latter being seldom reported in tattoos. We present a case of a predominantly T CLH, secondary to the black pigment of tattooing in a 35-year-old patient, with a dense infiltrate of small, medium and scarce large T-c...

 Abstract Castleman disease or giant node hyperplasia is a rare disorder of the lymphoid tissue most often involving the mediastinal lymph nodes. We report a case of localized retroperitoneal hyaline-vascular type of Castleman disease. A 35-year old woman presented with mild epigastric pain with radiation to the back. Amild anemia was the only abnormal associated finding. Abdominal ultrasound a...

A 32-year-old female case of large thymic hyperplasia with hyperthyroidism is reported. A computed tomography (CT) examination disclosed a large mediastinal mass (16 x 11 cm) with a heterogeneous internal structure containing both soft tissue density areas and fat density areas. The mass was histologically diagnosed as thymic lymphoid hyperplasia. The thymic mass enlarged during hyperthyroidism...

We report an unusual case of angioimmunoblastic T-cell lymphoma (AITL) progressing rapidly from Epstein-Bar virus (EBV)-associated paracortical hyperplasia with T-cell oligoclones, which caused the patient to die within only 1 month. The patient was a 67-year-old Chinese man with 3 month’s history of rhinorrhea, pruritus and superficial lymphadenopathy. In the first biopsy, morphology and immun...

We herein describe a rare case of multilocular thymic cysts (MTCs) with follicular hyperplasia. The patient was a 50-year-old man, who was symptom-free. A mediastinal mass was found on chest computed tomography (CT) followed after pancreatitis. Chest CT revealed a 30 × 10 mm anterior mediastinal mass with multiple cystic lesions. Magnetic resonance imaging showed an anterior mediastinal cystic ...

Epidermal hyperplasia is a protective response to restore disrupted skin barrier. Innate lymphoid cells (ILCs) have recently emerged as crucial resident immune for tissue homeostasis; however, how ILCs regulate the barrier after mechanical damage under physiological conditions remains unclear. In this study, we found that by mild tape stripping (T/S) induced epidermal with increased expression ...