The biochemical and morphological changes of the yeastlike (Y) form to the mycelial (M) form of Paracoccidioides brasiliensis were examined. The main polysaccharide of hexoses of the Y-form cell wall was alpha-glucan, whereas the polysaccharides of the M-form cell wall were beta-glucan and galactomannan. The alpha-glucan of the Y form contained mainly alpha-(1 --> 3)-glycosidic linkage. The bet...

This paper is concerned with the density-suppressed motility model: $$u_{t}=\Delta \left( \displaystyle \frac{u^m}{v^\alpha }\right) +\beta uf(w), v_{t}=D\Delta v-v+u, w_{t}=\Delta w-uf(w)$$ in a smoothly bounded convex domain $$\Omega \subset {{\mathbb {R}}}^2$$ , where $$m>1$$ $$\alpha>0, \beta >0$$ and $$D>0$$ are parameters, response function f satisfies $$f\in C^1([0,\infty )), f(0)=0, f(w...

BACKGROUND It has been shown that cells of the immune system release opioid peptides and possess receptors for them. The concentrations of opioid peptides in the peripheral circulation rapidly increase during inflammation and acute stress response. AIMS The effect of opioid peptides Met-enkephalin (M-ENK) and beta-endorphin (beta-END) on the oxidative metabolism of normal human neutrophils an...

We are interested in describing the infected size of SIS Epidemic model using Birth-Death Markov process. The Susceptible-Infected-Susceptible (SIS) is defined within a population constant $M$; kept by replacing each death with newborn healthy individual. life span individual modelled an exponential distribution parameter $\alpha$; and disease spreads Poisson process rate $\lambda_{I}$. $\lambd...

We introduce c-lasso, a Python package that enables sparse and robust linear regression classification with equality constraints. The underlying statistical forward model is assumed to be of the following form: \[ y = X \beta + \sigma \epsilon \qquad \textrm{subject to} C\beta=0 \] Here, $X \in \mathbb{R}^{n\times d}$is given design matrix vector $y \mathbb{R}^{n}$ continuous or binary response...

BACKGROUND Nosocomial infections caused by Pseudomonas aeruginosa presenting resistance to beta-lactam drugs are one of the most challenging targets for antimicrobial therapy, leading to substantial increase in mortality rates in hospitals worldwide. In this context, P. aeruginosa harboring acquired mechanisms of resistance, such as production of metallo-beta-lactamase (MBLs) and extended-spect...

An important component of amyloid fibrils in dialysis-related amyloidosis (DRA) is beta(2)-microglobulin (beta(2)m) modified with advanced glycation end products (AGE). The amyloid deposits are located principally in joint structures, with adjacent chronic inflammatory reaction characterized by monocyte infiltration. This study examined the interaction of AGE-beta(2)m with human synovial fibrob...

Endoglin, a transmembrane glycoprotein that acts as a transforming growth factor-beta (TGF-beta) coreceptor, is downregulated in PC3-M metastatic prostate cancer cells. When restored, endoglin expression in PC3-M cells inhibits cell migration in vitro and attenuates the tumorigenicity of PC3-M cells in SCID mice, though the mechanism of endoglin regulation of migration in prostate cancer cells ...