Periodontitis is one of the most common osteolytic inflammatory diseases in humans. Formation a periodontal bacteria-associated biofilm thought to be trigger for development periodontitis, but it not believed sufficient by itself sustain disease, as compromise host immune response critical tissue breakdown and disease progression. Macrophages play an important role both during initiation resolu...

Levamisole, an anthelminthic agent with immunostimulatory properties, does not alter in vitro macrophage-lymphocyte rosette formation between sheep alveolar macrophages and autochthonous lymphocytes.

Aggravation of atopic dermatitis (AD) is closely associated with excessive production cytokines by macrophages. To investigate the mechanisms how macrophages in human skin sense extracellular environment will help to understand diseases, however details remain unclear. In this study, we searched expression pattern 27 transient receptor potential (TRP) channels immune cells using protein atlas d...

Infection with human immunodeficiency virus type 1 (HIV-1) or T-lymphotropic I (HTLV-I) both can lead to mortality. CD4+T cells are the target for HTLV-I and HIV-1. In addition, HIV-1 infect macrophages. macrophages play important roles in immune system response. This article develops analyzes a discrete-time co-infection model. The model depicts within-host interaction of six compartments: uni...

The interaction of two types fragmented graphene particles (30–160 nm) with human macrophages is studied. Since have significant phagocytic activity, the incorporation into cells has an effect on response to functional polarization stimuli, favoring anti-inflammatory profile. Incubation foam particles, prepared by chemical vapor deposition, and commercially available nanoplatelet does not affec...

objective:cutaneous leishmaniasis is an endemic disease in some parts of iran.using pentavalent antimony compounds as first line treatment have been reported are associated with limitations and several adverse complications. so, attempt to find a new and effective compound has been under consideration.in the present study,the effect of achillea biebersteinii afanas that is a native plant in ira...

background: the present study was conducted to investigate the optimized timing for macrophages induction and nitric oxide (no) production against invading leishmania parasite. methods: the present study examined the murine macrophage cell line, b10r, in three different states. in the first state, the cells were first infected with l. major and then treated with ifn-g and lps as stimulants. in ...

background: the aim of the present study was to investigate the immunomodulation effects of aqueous garlic extract (age) in the cultured macrophages infected by leishmania major . methods: after j774 macrophages proliferation in rpmi1640 and incubation with leishmania for 72 hours, age was added in doses of 9.25, 18.5, 37, 74 and 148 mg/ml for 18, 24 and 48 hours and cell culture supernatants w...