BACKGROUND To investigate the efficacy of posterior subtenon methylprednisolone acetate injection in treatment of refractory diffuse clinically significant diabetic macular edema (CSME). METHODS In a prospective, nonrandomized, interventional case series, 52 eyes were diagnosed with CSME and treated with at least two sessions of laser photocoagulation according to Early Treatment Diabetic Ret...

Introduction Currently, three types of therapy are approved for the treatment of exudative age-related macular degeneration (AMD): laser photocoagulation, photodynamic therapy with Verteporfin and intravitreal injections of antiangiogenic agents (Ranibizumab and Pegaptanib). Other treatments revealed to be ineffective or even more aggressive than natural disease progression. Examples of these l...

Diabetic retinopathy remains a major cause of worldwide preventable blindness. Measures to avoid blindness include medical management (control of blood sugar, blood pressure, and serum lipids) and ocular management (laser photocoagulation and pars plana vitrectomy). Adjunctive pharmacologic therapies (intravitreal triamcinolone acetonide and anti-vascular endothelial growth factor agents) have ...

Treatment for diabetic macular edema (DME) is continuously evolving with the advent of pharmacologic therapies. Focal laser photocoagulation remains the historical standard of care; however, a new wave of studies is rapidly emerging that shows the benefit of intravitreal antivascular endothelial growth factor medications and corticosteroids. The goal of this review is to compare the various tre...

Diabetic macular edema (DME) remains an important cause of visual loss in patients with diabetes mellitus. Although photocoagulation and intensive control of systemic metabolic factors have been reported to achieve improved outcomes in large randomized clinical trials (RCTs), some patients with DME continue to lose vision despite treatment. Pharmacotherapies for DME include locally and systemic...

us to believe that there was indeed a treatment effect. Since reattachment ofthe retina and resolution ofthe macular hole was achieved solely with laser photocoagulation, we believe this should be the initial procedure in the management of these patients. 1 Reis W. Eine wenig bekannte typische missbildung am sehnerveneintritt: umnschiebene grubenbildung auf papilla n optici. ZeitschrAugenheilkd...

PURPOSE To utilize optical coherence tomography (OCT) and OCT angiography (OCTA) to describe alterations in the retinal and choriocapillaris vasculature following remote laser photocoagulation. Lesions are classified on the basis of choriocapillaris alteration as evaluated on en face OCTA. METHODS This was a retrospective, cross-sectional study analyzing 28 laser photocoagulation scars from 8...

Due to the significance of macular edema in retinal vascular diseases, this study aims determine whether laser photocoagulation is effective treatment and improvement visual acuity. This a prospective data considering 80 patients with 52 eyes, follow-up 6 weeks, 3 months, six months treated double frequency yag Aso Eye Hospital Sulaymaniyah City, Kurdistan, Iraq, from February 2010 October 2010...

Purpose To investigate the effect of the vascular adhesion protein-1 (VAP-1) inhibitor RTU-1096 on retinal morphologic changes and ocular inflammation after retinal laser photocoagulation in mice. Methods C57BL/6JJcl mice were fed a diet containing RTU-1096, a specific inhibitor for VAP-1, or a control diet ad libitum for 7 days. Laser photocoagulation was performed on the peripheral retina o...

PURPOSE To estimate the 3-year incidence of exudative age-related macular degeneration (AMD) and its treatment by laser photocoagulation in elderly Americans. DESIGN Population-based cohort study using insurance claims data. PARTICIPANTS A random 5% sample of Medicare beneficiaries, age 65 and older. METHODS Incidence of exudative AMD and of laser photocoagulation for this condition was a...