Phytopathogenic ascomycete fungi possess huge effector repertoires that are dominated by hundreds of sequence-unrelated small secreted proteins. The molecular function of these effectors and the evolutionary mechanisms that generate this tremendous number of singleton genes are largely unknown. To get a deeper understanding of fungal effectors, we determined by NMR spectroscopy the 3-dimensiona...

Derivatives of pyrazolo[1,5-a][1, 3, 5]triazine-2,4-dione,pyrazolo[1,5-c][1, 3, 5]thiadiazine-2-one, pyrazolo[3,4-d][1, 3]thiazine-4-one, and pyrazolo[3,4-d][1, 3]thiazine-4-thione were screened for antifungal activity against the causal agent of rice blast disease, Magnaporthe grisea. The compounds were tested at doses ranging from 10 to 200mugml(-1), using the commercial fungicide tricyclazol...

Accurate and sensitive detection of Magnaporthe oryzae infection in agricultural crops is utmost significance for effective management as well restricting the dispersion pathogen to new terrains. The research progress field molecular biology, computational biotechnology, nanotechnology have provided opportunities develop disease specific diagnostic procedures. At present, nucleic acid driven pr...

Abstract The mitotic exit network (MEN) pathway is a vital kinase cascade regulating the timely and correct progress of cell division. In rice blast fungus Magnaporthe oryzae , MEN pathway, consisting conserved protein kinases MoSep1 MoMob1-MoDbf2, important in development pathogenicity fungus. We found that deletion MoSEP1 affects phosphorylation MoMob1, but not MoDbf2, contrast to what was bu...