Replication of amyloid-based yeast prions [PSI(+)], [URE3], and [PIN(+)] depends on the protein disaggregation machinery that includes Hsp104, Hsp70, and Hsp40 molecular chaperones. Yet, overexpressing Hsp104 cures cells of [PSI(+)] prions. An Hsp70 mutant (Ssa1-21p) antagonizes propagation of [PSI(+)] in a manner resembling elevated Hsp104. The major cytosolic Hsp40 Sis1p is the only Hsp40 req...

Max Ludwig,1,2,* K. Hammerer,3 and Florian Marquardt1,2,4 1Department of Physics, Center for NanoScience, and Arnold Sommerfeld Center for Theoretical Physics, Ludwig-Maximilians-Universität München, Theresienstrasse 37, D-80333 Munich, Germany 2Institut für Theoretische Physik, Universität Erlangen-Nürnberg, Staudtstrasse 7, D-91058 Erlangen, Germany 3Institute for Quantum Optics and Quantum C...

Record: 1 Title: The market for feminist epistemology. Authors: Baber, Harriet Source: Monist; Oct94, Vol. 77 Issue 4, p403, 21p Document Type: Article Subject Terms: *KNOWLEDGE, Theory of *FEMINIST theory Abstract: Focuses on the feminist paradigm of epistemology. Failure of traditional theories of knowledge to account for features of women's experience; Empirical assumptions about gender diff...

Mandibular premolars often show aberrant anatomy varying from one to three canals. The incidence of occurrence of 3 canals has been recorded to be 0.46 - 0.5 %. We report a case of mandibular second premolar with 3 canals, which was initially diagnosed radiographically by shift cone technique and confirmed by clinical examination. The tooth was successfully obturated and restored. It remained a...

OBJECTIVE To evaluate the presurgical orthodontic tooth movement of mandibular teeth after dental decompensation for skeletal Class III deformities on the basis of vertical skeletal patterns. METHODS This cohort was comprised of 62 patients who received presurgical orthodontic treatment. These patients were divided into 3 groups according to their vertical skeletal patterns. Changes in the po...

Introduction: Congenital missing of maxillary lateral incisors and mandibular second premolars are one of the most common developmental dental anomalies that can affect patient’s function and aesthetics. The aim of this study was to determine the prevalence and pattern of congenital missing of lateral maxillary teeth and second mandibular premolars in patients referred to the Dental Faculty of ...

Kök kanal sisteminin; temizlenmesi, şekillendirilmesi ve doldurulması başarılı kök tedavisi için en önemli faktörlerdir. Mandibular premolar dişler genellikle tek kök, anatomisine sahiptir. Bu dişlerde farklı anatomisinin olması nadir görülmektedir. Farklı açılardan çekilen periapikal filmler ya da dental volümetrik bilgisayarlı tomografi kullanımıyla ilave kanallar teşhis edilebilir. Ayrıca en...