BACKGROUND A T-piece resuscitator (TPR) uses a built-in manometer to set the inflation pressures, but we are not informed what pressures are actually delivered distally. Aim of this study was to measure the proximal and distal pressures under different gas conditions when using a TPR. METHODOLOGY/FINDINGS A test lung was ventilated using a TPR (PIP 25 cmH₂O, PEEP 5 cmH₂O) with a gas flow rate...

BACKGROUND Cyclic redistribution of air within the cuff during respiratory pressure changes creates a self-sealing mechanism which allows tracheal sealing, despite tracheal airway pressure being above baseline cuff inflation pressure. The aim of the present study was to investigate the effect of continuous automated cuff pressure regulation on tracheal sealing during cyclic respiratory pressure...

BACKGROUND Cryptococcal meningitis is associated with increased intracranial pressure (ICP). Therapeutic lumbar puncture (LP) is recommended when the initial ICP is >250 mm H2O, yet the availability of manometers in Africa is limited and not always used where available. We assessed whether intraocular pressure could be a noninvasive surrogate predictor to determine when additional therapeutic L...

The muscular reactions of the mammalian ventricles to localized artificial stimuli have not been studied with the degree of precision that the subject merits. This is due partly to the fact that, until recently, we have possessed no graphic appliances capable of recording the ventricular contractions in an accurate manner. The details of the premature contraction curve, the latent period, the e...

STUDY OBJECTIVE Excessive pressure exerted on the tracheal mucosa is an avoidable factor implicated as a cause of damage after intubation of the trachea with cuffed tubes. Many patients are intubated in the out-of-hospital setting by emergency medical teams. The time spent in the out-of-hospital setting could very well be long enough for tracheal mucosal damage to occur if cuff pressure is not ...

On account of some undesirable features of the simplified Bunzel oxidase apparatus) the author has designed a simple apparatus (Fig. 1) incorporating the advantages of both the simplified Bunzel apparatus and the original design. 2 The simplified Bunzel oxidase apparatus makes no provision for the absorption of CO~ other than by the reagents used. In some reactions the CO2 production cannot be ...