The aim of this review is to provide information regarding significant aspects and challenges in developing nasal sprays. This article outlined the relevant anatomy, physiology & biological, physicochemical pharmaceutical factors that must be considered during formulation development Nasal drug delivery system most preferable route than other routes administration as it gives rapid onset ac...

Turmeric has been studied and used as a plant derivate active ingredient for centuries. Several effects of turmeric have described, however the poor solubility its ingredients during formulation development may limit oral applicability. The aim research was to involve dietary supplement hard capsule containing (Curcuma longa) (ground powder from root standardized curcuminoid content) sodium ben...

The aim of this work is to understand the effects of the rheological and interfacial properties of a model food on continuous foaming operation in laminar flow conditions. The rheological properties of food model (glucose syrup) were adjusted using three polysaccharides: xanthan, LM pectin and guar. Interfacial properties were varied using two kinds of proteins: Na-caseinates and whey proteins ...

Purpose: In the newly released ASTM standard specification for Additive Manufacturing File (AMF) format – version 1.1, Hermite curve based interpolation is employed to refine input triangles to generate denser mesh with smoother geometry. This paper studies the problems of constructing smooth geometry based on Hermite interpolation on curves and proposes a solution to overcome these problems. D...

This paper deals with the problem of finding optimal feeding sequence in a manufacturing cell with feeders fed by a mobile robot with manipulation arm. The performance criterion is to minimize total traveling time of the robot in a given planning horizon. Besides, the robot has to be scheduled in order to keep production lines within the cell working without any shortage of parts fed from feede...

Background Variability in probiotics manufacturing may affect their properties, with potential implications for their efficacy and safety. This is of particular concern with probiotic products destined for use in patients with serious medical conditions, including human immunodeficiency virus (HIV) infection. The purpose of the study was to carry out a series of experiments comparing the proper...