The cell surface of fungi, bacteria, and sea organisms is highly glycosylated. These glycans are oligo-or polysaccharide molecules that can be secreted or attached to protein or lipids forming glycoconjugates. They present extraordinary structural diversity that could explain their involvement in many fundamental cellular processes, including growth, differentiation, and morphogenesis. Consider...

Objective: The potential of marine crabs as a source of bioactive products is largely unexplored. Methods: Portunussegnis crabs were collected from the northern coast of Persian Gulf. Antimicrobial activities of hepatopancreas, hemolymph and proteins of hemplymph from P. segnis crabs against a range of 11 different bacterial and 6 fungal pathogen strains were examined. Two positive controls Amo...

Dry mouth is a troublesome condition linked to lubrication failure and leads other diseases such as fungal infections wounds in the oral cavity. There are many commercial salivary substitutes market, but none with long-lasting effect. Polymer-coated liposomes can be an interesting formulation strategy for retrieving symptoms of dry by mimicking micelles saliva. In present study, polymer coated-...

BACKGROUND The glucuronoyl esterase enzymes of wood-degrading fungi (Carbohydrate Esterase family 15; CE15) form part of the hemicellulolytic and cellulolytic enzyme systems that break down plant biomass, and have possible applications in biotechnology. Homologous enzymes are predicted in the genomes of several bacteria, however these have been much less studied than their fungal counterparts. ...

Four new nitroasterric acid derivatives, pseudogymnoascins A-C (1-3) and 3-nitroasterric acid (4), along with the two known compounds questin and pyriculamide, were obtained from the cultures of a Pseudogymnoascus sp. fungus isolated from an Antarctic marine sponge belonging to the genus Hymeniacidon. The structures of the new compounds were determined by extensive NMR and MS analyses. These co...

Molecular diversity surveys have demonstrated that aquatic fungi are highly diverse, and that they play fundamental ecological roles in aquatic systems. Unfortunately, comparative studies of aquatic fungal communities are few and far between, due to the scarcity of adequate datasets. We combined all publicly available fungal 18S ribosomal RNA (rRNA) gene sequences with new sequence data from a ...

The present work describes the biological activities using the marine sponges collected from kanyakumari. The sponges are such as the Callyspongia diffusa, Echinodictyum gorgonoides, Callyspongia reticutis, Gelliodes cellaria, and Thalysias vulpine. It is revealed that the sponges showed the antifungal activity against the various fungal strains such as the Aspergillus niger, Pencillium notatum...

Natural products from fungi, especially Ascomycota, play a major role in therapy and drug discovery. Fungal strains originating from marine habitats offer a new avenue for finding unusual molecular skeletons. Here, the marine-derived fungus Epicoccum nigrum (strain 749) was found to produce the azaphilonoid compounds acetosellin and 5',6'-dihydroxyacetosellin. The latter is a new natural produc...

Methanol is a byproduct of cell wall modification, released through the action of pectin methylesterases (PMEs), which demethylesterify cell wall pectins. Plant PMEs play not only a role in developmental processes but also in responses to herbivory and infection by fungal or bacterial pathogens. Molecular mechanisms that explain how methanol affects plant defenses are poorly understood. Here we...