Breast cancer continues to be a significant public health problem in the world. Early detection is the key for improving breast cancer prognosis. Mammography is currently the primary method of early detection. But recent research has shown that many cases missed by mammography can be detected in Breast DCE-MRI. Magnetic Resonance (MR) imaging is emerging as the most sensitive modality that is c...

Broadly speaking, the objective in cardiac image segmentation is to delineate the outer and inner walls of the heart to segment out either the entire or parts of the organ boundaries. This paper will focus on MR images as they are the most widely used in cardiac segmentation – as a result of the accurate morphological information and better soft tissue contrast they provide. This cardiac segmen...

Models of geometry or appearance of three-dimensional objects may be used for locating and specifying object instances in 3D image data. Such models are necessary for segmentation if the object to be segmented is not separable based on image information only. They provide a-priori knowledge about the expected shape of the target structure. The success of such a segmentation task depends on the ...

Abstract. The Mumford-Shah model is one of the most important image segmentation models, and has been studied extensively in the last twenty years. In this paper, we propose a two-stage segmentation method based on the Mumford-Shah model. The first stage of our method is to find a smooth solution g to a convex variant of the Mumford-Shah model. Once g is obtained, then in the second stage, the ...

Combining image segmentation based on statistical classification with a geometric prior has been shown to significantly increase robustness and reproducibility. Using a probabilistic geometric model of sought structures and image registration serves both initialization of probability density functions and definition of spatial constraints. A strong spatial prior, however, prevents segmentation ...

In recent years, matrix-assisted laser desorption/ionization (MALDI)-imaging mass spectrometry has become a mature technology, allowing for reproducible high-resolution measurements to localize proteins and smaller molecules. However, despite this impressive technological advance, only a few papers have been published concerned with computational methods for MALDI-imaging data. We address this ...

Combining image segmentation based on statistical classification with a geometric prior has been shown to significantly increase robustness and reproducibility. Using a probabilistic geometric model of sought structures and image registration serves both initialization of probability density functions and definition of spatial constraints. A strong spatial prior, however, prevents segmentation ...