Sharp trauma is an injury resulting in wounds on the surface of body by sharp objects. comprosised three forms wounds, namely incised (vulnus scissum), stab punctum), and chopped caesum). Cardiac damage caused to heart which not congenital or degenerative nature but impact/physical collision from outside can reduce change consciousness lead cognitive abilities, physical function, death. In this...

We report a noteworthy case of a 7-month-old infant who suddenly and unexpectedly died during her sleep. After a complete postmortem examination, review of the clinical history, and detailed death scene investigation, the death remained unexplained, leading to a diagnosis of sudden infant death syndrome. However, an extensive review of the brainstem neuropathology revealed a severe alteration i...

To directly examine the role of vascular endothelial growth factor (VEGFA) in cartilage development, we conditionally knocked out Vegfa in chondrocytes, using the Col2a1 promoter to drive expression of Cre recombinase. Our study of Vegfa conditional knockout (CKO) mice provides new in-vivo evidence for two important functions of VEGFA in bone formation. First, VEGFA plays a significant role in ...

Multiple mycotic pseudoaneurysms of the aorta are rarely seen. This case summarizes a patient who survived primary rupture of his proximal ascending aortic pseudoaneurysm but was an unacceptable candidate for surgical therapy. He survived for approximately four months prior to death from massive hemoptysis. The case presents a rare look at an unusual condition and the difficulties in the manage...

Pulmonary veno-occlusive disease (PVOD) occurred in a six-year-old girl. Investigation of a number of proposed causes for this uncommon condition and histologic progression of disease are documented. To our knowledge, this is the first case of PVOD in which death was due to massive alveolar hemorrhage.

trauma is a common cause of death and disability in children. proper approach to pediatric trauma involves adherence to abcde sequence in the primary survey and resuscitation in order to promptly recognize and manage life-threatening conditions immediately. this readily reviewed sequence includes a: establishment and maintenance of a patent airway while maintaining cervical spine immobilization...