BACKGROUND Several genetic factors underlying ischemic stroke have been identified. Variants of Neuropeptide Y (NPY), whose product plays diverse roles in modulating physiological functions, have been associated with an increased risk of ischemic stroke in South Korean individuals. AIMS We explored the association between a polymorphism in the NPY gene promoter at position -399 and the risk o...

Atrial fibrillation (AF) is a major risk factor for ischemic stroke and associated with a 5-fold higher risk of stroke. In this retrospective cohort study, the incidence of and risk factors for ischemic stroke in patients with AF were identified. All patients (≥30 years old) without previous stroke who were diagnosed with AF in 2007-2013 were selected from the National Health Insurance Service-...

BACKGROUND To compare the characteristics and prognostic features of ischemic stroke in patients with diabetes and without diabetes, and to determine the independent predictors of in-hospital mortality in people with diabetes and ischemic stroke. METHODS Diabetes was diagnosed in 393 (21.3%) of 1,840 consecutive patients with cerebral infarction included in a prospective stroke registry over ...

Introduction: Elevated levels of CRP are present among patients at risk for further first-ever myocardial infarction and stroke. It has been shown that after ischemic stroke, increased levels of CRP are associated with unfavorable outcomes. Methods: From 120 patients admitted to the emergency unit of our hospital with the diagnosis of stroke CRP, D-dimer and ferritin level was measured and the ...

COVID-19 is typically a respiratory or lung infection however the SARS-CoV-2 virus has been found to cause blood clots leading stroke. The World Stroke Organization reported 5% risk for an ischemic stroke in setting of

Acute ischemic stroke is a time-sensitive emergency requiring rapid accurate diagnosis and treatment. Stroke Mimic (SM) noncerebrovascular condition that presents with acute focal neurological deficts masquerades

BACKGROUND The aim of this study was to analyze the benefits and safety associated with the combination therapy of clopidogrel and aspirin among minor stroke or transient ischemic attack patients treated within 12 hours. METHODS AND RESULTS This was a subanalysis of the CHANCE (Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events) trial, mainly limited to the presp...

introduction: transforming growth factor-beta 1 (tgf-β1) is a pleiotropic cytokine with potent anti-inflammatory property, which has been considered as an essential risk factor in the inflammatory process of ischemic stroke (is), by involving in the pathophysiological progression of hypertension, atherosclerosis, and lipid metabolisms. -509c/t tgf-β1 gene polymorphism has been found to be assoc...

BACKGROUND AND PURPOSE The decision to prescribe oral anticoagulant therapy in patients with atrial fibrillation is based on an assessment of the competing risks of ischemic stroke and major bleeding, of which intracerebral hemorrhage (ICH) is the most important type. We sought to determine the comparative importance of risk factors for ischemic stroke and ICH in patients with acute stroke and ...

OBJECTIVE Patients with rheumatoid arthritis (RA) are at an increased risk of ischemic stroke. Tumor necrosis factor inhibitors (TNFi) may influence risk and mortality after ischemic stroke by reducing inflammation. This study was undertaken to examine the association of TNFi with the risk of incident ischemic stroke and with 30-day and 1-year mortality after ischemic stroke. METHODS Patients...