the goal of this talk will be to familiarize the audience with the nature and prevalence of anxiety disorders and document their impact on society. anxiety is the most common form of psychopathology affecting an estimated one in four people at some point during their lifetimes. in comparison to all types of diseases and injuries, a 2013 jama report indicated that anxiety disorders were the fift...

BACKGROUND Identifying the unique and shared premorbid indicators of risk for the schizophrenia spectrum disorders (SSD) and affective psychoses (AP) may refine aetiological hypotheses and inform the delivery of universal versus targeted preventive interventions. This systematic review synthesises the available evidence concerning developmental risk factors and antecedents of SSD and AP to iden...

Abstract The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative model psychopathology. HiTOP proposes that trauma-related distress facet Internalizing psychopathology, but recent evidence with young people suggests it may reflect unique dimension This study assessed the latent structure child and adolescent psychopathology to determine whether there ‘Traumatic Stress’ dimension,...

To determine the relationship between the genetic and environmental risk factors for externalizing psychopathology and mental wellbeing, we examined detailed measures of emotional, social and psychological wellbeing, and a history of alcohol-related problems and smoking behavior in the last year in 1,386 individual twins from same-sex pairs from the MIDUS national US sample assessed in 1995. Ch...

BACKGROUND Several studies showed that maternal smoking in pregnancy is related to behavioural and emotional disorders in the offspring. It is unclear whether this is a causal association, or can be explained by other smoking-related vulnerability factors for child behavioural problems. METHODS Within a population-based birth cohort, both mothers and fathers reported on their smoking habits a...

Examined correlates of treatment response in a clinic providing cognitive-behavioral therapy for children with anxiety disorders. Youth (ages 7 to 15) with a primary Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev., or 4th ed.; American Psychiatric Association, 1987, 1994) anxiety-disorder diagnosis (overanxious disorder, generalized anxiety disorder, separation anxiety diso...

BACKGROUND As children with velocardiofacial syndrome (VCFS) develop, they are at increased risk for psychopathology; one third will eventually develop schizophrenia. Because VCFS and the concomitant symptomatology result from a known genetic origin, the biological and behavioral characteristics of the syndrome provide an optimal framework for conceptualizing the associations among genes, brain...

A large body of literature documents the adverse effects of maternal depression on the functioning and development of offspring. Although investigators have identified factors associated with risk for abnormal development and psychopathology in the children, little attention has been paid to the mechanisms explaining the transmission of risk from the mothers to the children. Moreover, no existi...