conclusions this study found that gbv-c infection has a high frequency among injecting drug users with hiv/hcv coinfection and hcv mono-infection in yunnan, china. in patients with chronic hepatitis c and hiv coinfection, gbv-c rna was associated with significantly lower alt and ast levels, suggesting a beneficial effect of gbv-c infection on chronic hepatitis c. results gbv-c rna was identifie...

It is estimated that the number of HIV infected children globally has increased from 1.6 million in 2001 to 3.3 million in 2012. The number of children below 15 years of age living with HIV has increased worldwide. Published data from recent studies confirmed dramatic survival benefit for infants started anti-retroviral therapy (ART) as early as possible after diagnosis of HI. Early confirmatio...

Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...

A MATHEMATICAL GROWTH MODEL OF THE VIRAL POPULATION IN EARLY HIV-1 INFECTIONS SEPTEMBER 2011 ELENA EDI GIORGI, ”Laurea,” UNIVERSITA’ DI PISA M.S., UNIVERSITY OF MASSACHUSETTS AMHERST M.S., UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES Ph.D., UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Panayotis Kevrekidis In this thesis we develop a mathematical model to describe HIV-1 evolution ...

The spread of human immunodeficiency virus (HIV) infection and the resulting acquired immune deficiency syndrome (AIDS) is a major health concern in many parts of the world, and mathematical models are commonly applied to understand the spread of the HIV epidemic. To understand the spread of HIV and AIDS cases and their parameters in a given population, it is necessary to develop a theoretical ...

In most countries, educational programs and condom use is recommended as the most important approaches in controlling HIV infection. We examine the role of different approaches in controlling AIDS epidemics in our region. We find a high failure rate and probably undesirable effects for condom recommendation in epidemiological scale especially considering the low prevalence of HIV infection ...