The influence of mixed hematopoietic chimerism (MC) after allogeneic bone marrow transplantation remains unknown. Increasingly sensitive detection methods have shown that MC occurs frequently. We report a highly sensitive novel method to assess MC based on the polymerase chain reaction (PCR). Simple dinucleotide repeat sequences called microsatellites have been found to vary in their repeat num...

Mitomycin C (MC) is a chemically reactive antibiotic derived from Streptomyces caespitosus. The drug selectively inhibits DNA synthesis (2, 15, 29, 34, 39, 40, 43, 44, 49) and degrades cellular DNA but does not affect the synthesis of R N A or protein (31, 33, 40). MC induces bacteriophage production in lysogenic bacteria (23, 29), increases the rate of genetic recombination among mutant forms ...

BACKGROUND Recent reports have documented greater mortality for bariatric surgery in Medicare (MC) patients compared with patients from other payors. METHODS We reviewed our database for the mortality and outcomes of 282 MC and 3169 non-Medicare (NMC) patients undergoing bariatric surgery. RESULTS Of the MC patients, 27 were >65 years of age, and 255 were receiving disability. The average a...

Mast cells (MC) are source of many biological active compounds like cytokines, arachidonic acid derivates, proteoglicanes, prostaglandins, proteases, free oxygen radials, NGF, PAF and many more. The role of MC in pathogenesis of Hirschsprung's disease (HD) is not clear. Substances produced by MC may exert an important effect on embryology, growth, differentiation and regeneration of intestinal ...

Induction of UDP-glucuronosyltransferases (UGTs) toward thyroxine (T4) and p-nitrophenol (pNP) by 3-methylcholanthrene (MC), dexamethasone (DEX), clofibrate (Cl), and MC combined with DEX or Cl was studied in rat hepatocyte culture. We have developed a sensitive method for the measurement of glucuronide conjugates of the two substrates based on HPLC analysis of culture medium. MC, Cl, or DEX in...

Two muconate cycloisomerases (MC I and MC II, EC 5.5.1.1> were purified to homogeneity from a" anilinegrown R'ateuria sp. ANA-18. MC I and MC II were similar in molecular mass, optimal pH, and pH stability but differny ent in thermostability, and some other enzymatic properties. NH2-terminal amino acid sequences were different between the twe isozymes, indicated that these are encoded by differ...

Emulsions are widely used in food industry, among others. Monosized droplets in emulsions have advantages for control of their properties, and application fields. We have developed microchannel emulsification (MC) technology for monosized droplets formation. The grooved type MC and module were used to characterize MC emulsification, and straight-through MC and module were developed for higher p...

Odor signals are transmitted to the olfactory bulb by olfactory nerve (ON) synapses onto mitral/tufted cells (MCs) and external tufted cells (ETCs). ETCs, in turn, provide feedforward excitatory input to MCs. MC and ETCs are also regulated by inhibition: intraglomerular and interglomerular inhibitory circuits act at MC and ETC apical dendrites; granule cells (GCs) inhibit MC lateral dendrites v...

• Vertebral endplate changes/modic changes (MC) are the MRI-images of inflammatory vertebral endplate damage that are often related to general disc degeneration. • In patients with prolonged back pain, the prevalence of MC is 40%. • In individuals with MC, more than 90% will have back pain within 1 year. • MC often causes localized pain 24/7. • Nocturnal pain is the rule rather than the excepti...

INTRODUCTION The main extra-hepatic manifestation of hepatitis C is mixed cryoglobulinemia (MC). The aim of this study was to evaluate its prevalence among patients with chronic hepatitis C (CHC), to correlate its presence to host and virological variables and to the response to combined therapy with interferon-alpha and ribavirin. CASUISTIC AND METHODS 202 CHC naive patients (136 with chroni...