To account for particle interactions in the extracellular (physical) environment, information from the cell-level Monte Carlo damage simulation (MCDS) for DNA double strand break (DSB) induction has been integrated into the general purpose Monte Carlo N-particle (MCNP) radiation transport code system. The effort to integrate these models is motivated by the need for a computationally efficient ...

introduction bnct is an effective method to destroy brain tumoral cells while sparing the healthy tissues. the recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. in this paper, it is indicated that using d-t neutron source and optimizing of beam shaping assembly (bsa) leads to treating brain tumors in a reasonable time where all iaea ...

Background: The aim of this study was to develop and implement a Monte Carlo framework for evaluation of patient specific out-of-field organ equivalent dose (OED). Materials and Methods: Dose calculations were performed using a Monte Carlo-based model of Oncor linac and tomographic phantoms. Monte Carlo simulations were performed using EGSnrc user codes. Dose measurements were performed using r...

introduction the gamma knife system is designed solely for non-invasive treatment of brain disorders, and it benefits from stereotactic surgical techniques. dose calculations required in the system are performed by gammaplan code; in this code, brain tissue is considered uniform. in the present study, we evaluated the effect of gamma knife system on the obtained dose through simulating a real h...

background: for an effective treatment planning in brachytherapy, it is necessary to know the accurate source dosimetric information such as air kerma strength, exposure rate constant, dose rate constant and redial dose distribution. the usual method to determine these factors is thermo luminescent dosimeter (tld) dosimetry. nowadays, another more accurate method is known to be the monte carlo ...

background: two protocols of aapm tg-51 and iaea trs-398 were compared followed by a measurement and monte carlo simulation of beam quality correction factor, kq, aapm tg-51 and iaea trs-398 protocols were compared for the absorbed dose to water for dw, and kq parameters. materials and methods: dose measurements by either protocols were performed with cylindrical and plane parallel chambers for...