A rationale for clinical trials of hydroxyurea (HU) treatment in sickle cell disease is that the agent increases red blood cell (RBC) fetal hemoglobin content. However, an additional effect of HU is to raise the mean corpuscular volume (MCV). To investigate the action of HU in a species that makes no electrophoretically distinguishable fetal hemoglobin, we treated dogs with the drug and compare...

Abstract The São Gonçalo Channel, located in the south of Brazil, is responsible for connecting Mirim Lagoon to Patos Lagoon, constituting largest coastal lagoon system Latin America. assessment its hydraulic variables necessary given importance this channel region. Thus, study aimed evaluate performance index velocity rating curve (IVRC) method, from measurements provided by horizontal static-...

We analyzed the relationship between motor nerve conduction velocity (MCV) and morphological changes in regenerating nerve fibers at different times after sciatic nerve transection to identify reliable indices of functional recovery. Thirty rats were divided into five equal groups, one control group and four groups subjected to sciatic nerve transection and immediate suturing, followed by regen...

BACKGROUND/AIMS This study determined the prevalence and determinants of seropositivity for rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) antibody, and anti-mutated citrullinated vimentin (anti-MCV) antibody in unaffected first-degree relatives (FDRs) of rheumatoid arthritis (RA) patients. METHODS A total of 337 subjects (135 with RA and 202 FDRs) were enrolled in this ...

In this article, we propose a novel model to overcome the drawbacks of the modified Chan–Vese (MCV) model. Our model is devoted to find an optimal partition of inhomogeneous regions accurately and computationally efficient. MCV model was proposed on the concept of using one level-set function for one region. It needs fewer numbers of iterations and improves the efficiency of image segmentation ...

OBJECTIVE The aim of the present study was to investigate the relationship between iron, ferritin, transferrin, total iron binding capacity (TIBC), hemoglobin, mean corpuscular volume (MCV) mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in children with ADHD. METHODS MethodsaaThe sample consisted of 48 ADHD children and sex and age matched control chil...