The delayed release and mucoadhesive properties of Cedrela gum and hydroxypropylmethylcellulose blend in diclofenac sodium tablet formulations were evaluated. Tablets were prepared by direct compression and the crushing strength and detachment force were found to increase from 74.49 ± 1.22 to 147.25 ± 2.57 N and 0.302 ± 0.36 to 1.141 ± 0.05 N from low to high level of polymers, respectively. Th...

This study set out to assess the respirable mass, surface area, and number concentrations of the alpha-quartz content particles (C(r-m), C(r-s) and C(r-n)) to which workers were exposed in six different exposure groups, the raw material handling (n=10), crushing (n=12), mixing (n=12), forming (n=10), furnace (n=10), and packaging (n=10), in a refractory material manufacturing plant. For C(r-m),...

The dynamic response mechanism of the rock fragmentation and its influential factors by TBM disc cutter are studied in this paper. Firstly, a dynamic response model is established based on the fracture mechanics and finite element theory. Secondly, a fragmentation rule is founded according to the dynamic response model, and then numerical simulations for dynamic response of rock are carried out...

Mammalian molluscivores feed mainly by shell-crushing or suction-feeding. The extinct marine arctoid, Kolponomos, has been interpreted as an otter-like shell-crusher based on similar dentitions. However, neither the masticatory biomechanics of the shell-crushing adaptation nor the way Kolponomos may have captured hard-shelled prey have been tested. Based on mandibular symphyseal morphology shar...

We show a global existence theorem for Einstein-matter equations of T -Gowdy symmetric spacetimes with stringy matter. The areal time coordinate is used. It is shown that this spacetime has a crushing singularity into the past. From these results we can show that the spacetime is foliated by compact hypersurfaces of constant mean curvature. PACS: 02.03.Jr, 04.20.DW , 04.20.EX, 98.80.HW Present ...

We show a global existence theorem for Einstein-matter equations of T -Gowdy symmetric spacetimes with stringy matter. The areal time coordinate is used. It is shown that this spacetime has a crushing singularity into the past. From these results we can show that the spacetime is foliated by compact hypersurfaces of constant mean curvature. PACS: 02.03.Jr, 04.20.DW , 04.20.EX, 98.80.HW Present ...

Abstract The use of additive manufacturing for the fabrication sacrificial cladding is becoming increasingly popular as it facilitates production complex yet space-saving protective structures. Despite this, effect several structural parameters on their capacity to mitigate high-velocity impacts remains elusive. Toward this end, shock-mitigating various short fiber-reinforced polymer samples wa...

Abstract This work investigates the impact of infill pattern structure on crashworthy performance and deformation history 3D-printed tubes subjected to a quasi-static axial compression load. The proposed were made from polylactic acid (PLA) using 3D printing technique. Five structures adapted, i.e. circular, square, triangle, zigzag cross patterns with 50% density. analysis was carried out by a...