BACKGROUND Although chemotherapy and radiation treatment have contributed to increased survivorship, treatment-induced brain injury has been a concern when examining long-term intellectual outcomes of survivors. Specifically, disruption of brain white matter integrity and its relationship to intellectual outcomes in adult survivors of childhood brain tumors needs to be better understood. METH...

The neuroprotective effects of physical activity (PA) are consistently shown in older adults, but the neural substrates, particularly in white matter (WM), are understudied, especially in very old adults with the fastest growth rate and the highest risk of dementia. This study quantified the association between PA and WM integrity in adults over 80. The moderating effects of cardiometabolic con...

BACKGROUND AND PURPOSE Hypertension is a risk factor for cerebral small vessel disease, which includes white matter lesions (WML) and lacunar infarcts. These lesions are frequently observed on MRI scans of elderly people and play a role in cognitive decline. Preferably, one would like to evaluate the effect of hypertension before fluid-attenuated inversion recovery visible macrostructural lesio...

OBJECTIVE To investigate the relationship of white matter integrity and path of the corticospinal tract (CST) on arm function before and after constraint-induced (CI) movement therapy in children with hemiparetic cerebral palsy (CP) and adults with chronic stroke. DESIGN Study 1 used a multiple-baseline pre-post design. Study 2 was a randomized controlled trial. SETTING Outpatient rehabilit...

the objective of this study was to diagnose integrative ecological health of an urban stream,which is located in the asian temperate region. the research approach was primarily based on the index ofbiological integrity (ibi) using fish assemblage and a qualitative habitat evaluation index (qhei). and these indexes were compared with long-term conventional chemical dataset during 1996-2005. for ...