The ubiquitous presence of solar UV radiation in human life is essential for vitamin D production but also leads to skin photoaging, damage, and malignancies. Photoaging and skin cancer have been extensively studied, but the effects of UV on the critical mechanical barrier function of the outermost layer of the epidermis, the stratum corneum (SC), are not understood. The SC is the first line of...

While nanoparticles exert bactericidal effects through the generation of reactive oxygen species (ROS), the processes of the internalization of and the direct physical damage caused by iron oxide nanoparticles are not completely clear. We hypothesize that direct physical or mechanical damage of the cell membrane and cytoplasmic integrity by nanoparticles is another major cause of bacterial deat...

INTRODUCTION Since the introduction of ceramic brackets, research has been performed to evaluate enamel damage caused during their removal. One problem in comparing treated and control groups is the absence of assurance that the surfaces were undamaged before the brackets were bonded and debonded, or that superficial treatment applied to the enamel could hinder damage detection. The aim of this...

Any attempt made to separate energy into electrical and mechanical parts may lead to inconsistencies as they do not necessarily decouple. This is illustrated by application of the energy density function in the linear theory of piezoelasticity. By assuming that a critical energy density function prevails at the onset of crack initiation, it is possible to establish the relative size of an inner...

BACKGROUND Cervical dilation using mechanical dilators is associated with various complications, such as uterine perforation, cervical laceration, infections and intraperitoneal hemorrhage. To achieve safe and painless cervical dilation, we constructed a new medical device to achieve confident mechanical cervical dilation: a continuous controllable balloon dilator (CCBD). METHODS Controlled p...

The goal of damage-mitigating control is to achieve high performance of operating machinery without overstraining the mechanical structures and the potential benefit is an increase in the component service life with no significant loss of performance. This paper presents the design of a test apparatus, the synthesis of a damage-mitigating control system, and the results of experimentation where...

The response to mechanical damage is crucial for the survival of multicellular organisms, enabling their adaptation to hostile environments. Trichoderma atroviride, a filamentous fungus of great importance in the biological control of plant diseases, responds to mechanical damage by activating regenerative processes and asexual reproduction (conidiation). During this response, reactive oxygen s...

The harvesting of processing tomatoes is fully mechanised and it is well known that during harvest, fruits are subjected to mechanical stress causing physical injuries, including skin punctures, pulp and cell rupture. Some wireless sensors have been used for research during recent years with the main purpose of reducing the quality loss of tomato fruits by diminishing the number and intensity o...

Quasi-static and dynamic compression and three-point bending tests have been carried out on Strombus gigas (conch) shells. The mechanical response is correlated with its microstructure and damage mechanisms. The mechanical response is found to vary significantly from specimen to specimen and requires the application of Weibull statistics in order to be quantitatively evaluated. The conch exhibi...

M echanical ventilation is the most widely used therapy in intensive care units and the cornerstone treatment for patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) [1]. Although essential for successful management of respiratory failure, mechanical ventilation can also exacerbate or even directly injure the lungs [2, 3]. This damage, commonly referred to as ve...