نتایج جستجو برای: medicinal chemistry
تعداد نتایج: 143302 فیلتر نتایج به سال:
1 Department of Organic Chemistry, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, Egypt. 2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt. 3 Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt. 4 Department of Pharmaceutical Organic chemistry, Faculty of Pharmacy, Beni-suef Un...
In continuation of Nepalese medicinal plant screening research, we have examined the antibacterial property of 40 methanol crude extracts in vitro using disc diffusion method against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis. Overall, 95 % of the extracts showed antibacterial activity against at least one Gram-negative bacteria and 90 % of the extract...
Medicinal plants are considered as key sources of drugs for the treatment of various ailments worldwide. The flora of Pakistan due to its highly favorable diverse climatic and soil conditions, many topographical regions and ecological zones offer a great variety of medicinal plants [1]. According to a general survey, approximately 6000 flowering plants exist in Pakistan, out of which 400-600 ar...
Objectives: Systemic arterial hypertension is a multifactorial clinical condition, characterized by sustained high levels of blood pressure. The secondary metabolites of medicinal plants may work in part through modification of haemodynamics including blood pressure alteration. This study aimed to conducted a literature review of medicinal plants that can cause blood pressure changes and intera...
Inflammation is part of the body's immune response. There can be four primary indicators of inflammation: pain, redness, heat or warmness and swelling. Plants have the ability to synthesize a wide verity of phytochemical compounds as secondary metabolites which shows anti-inflammatory activity. In the present review an attempt has been made to investigate the anti-inflammatory activity of some ...
Therapeutic effects through G protein-coupled receptors (GPCRs) are promoted by a full agonist, partial agonist, neutral antagonist or inverse agonist. Dramatic change of function such as from a neutral antagonist to a full agonist with minimal variation of ligand structure is a phenomenon that medicinal chemists often encounter. This is also influenced by a change of assay format. The subtle n...
Med. Chem. Com This journal is © The Royal Society of Chemistry 2015 Georg-August-University Göttingen, Department of Chemistry, Institute of Organic and Biomolecular Chemistry, Tammannstr. 2, 37 077 Göttingen, Germany. E-mail: [email protected] b Saarland University, Department of Pharmacy, Pharmaceutical and Medicinal Chemistry, Campus C2 3, 66 123 Saarbrücken, Germany † Electro...
In the field of medicinal chemistry, Quinazolinone is a heterocyclic compound having unique place which has medicinal uses as Anticancer, antihypertensive, antihyperlipidemic, antitubercular, CNS depressant, antioxidant, analgesic, antibacterial, anti-inflammatory and antimalarial activity. Quinazolinone based drugs have broadened scope in the field of medicine and Research. Some quinazolinone ...
From the ‡Center for Experimental Therapeutics and Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6160, the ¶Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland 20892, the Department of Microbiology, School of Pharmaceutical Sciences, Showa Unive...
*National Institute of Mental Health Psychoactive Drug Screening Program, and Departments of †Biochemistry, ‡Psychiatry, §Neurosciences, and ‡‡Pharmacology and Nutrition, Case Western Reserve University Medical School, Cleveland, OH 44106; §§Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224; Dep...
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