Nail melanoma (NM) must be suspected in the initial workup of patients with pigmented nails. However, differential diagnosis NM from other nail disorders that involve pigmentation is challenging. Dermoscopic, clinical, and histopathological features are integrated for a definite diagnosis. The primary treatment surgery. Depending on depth invasion, amputation or functional surgery can chosen. T...

Abstract Malignant melanoma is considered to be one of the deadliest types skin cancer, and it responsible for death a large number people worldwide. However, distinguishing whether benign or malignant has been challenging task. Many Computer Aided Diagnosis Detection Systems have developed in past this This paper presents deep learning framework based approach diagnosis recognition. In propose...

The incidence of melanoma has been on the rise for the last several decades, with a current US lifetime risk of developing melanoma estimated as 1 in every 60 individuals [1]. The key to preventing death from melanoma is the early detection of this cancer, at a stage where surgical excision is curative. However, in attempt to diagnose melanoma early, physicians are also removing many benign les...

Some cutaneous melanocytic lesions are notoriously difficult to diagnose by histopathology. For that reason, the Pathology Panel of the Dutch Melanoma Working Party was instituted and is regularly approached to provide an expert opinion on problem cases. In order to identify the most common diagnostic problems, 1069 consecutive referral cases of submitted lesions (1992 to 1994 inclusive) were a...

A 38-year-old male presented to our hospital with the chief complaint of chronic cough. Eight years previously he was diagnosed with cilioretinal malignant melanoma and underwent left ophthalmectomy. On chest CT, pleural effusion and diffuse thickening of left pleura were suspected (Picture 1). The differential diagnosis included mesothlioma and metastatic melanoma. In thoracoscopic findings mu...

BACKGROUND Fine needle aspiration is an accurate technique to diagnose metastatic melanoma. Few reports exist in the literature describing its usefulness in many patients with melanoma confirmed by open biopsy. OBJECTIVE The purpose of this study was to determine the utility and predictive value of fine needle aspiration in patients with malignant melanoma who presented with lesions suspected...

Patients who are already diagnosed with cutaneous melanoma are at increased risk of developing another primary melanoma. The occurrence of multiple primary melanoma is a rare phenomenon, varying in frequency, with an estimated incidence ranging from 0.2% to 8.6%. The authors are presenting data on the patients with multiple primary melanoma from the Croatian Referral Melanoma Centre. The clinic...