We consider the problem of prediction of stationary time series, using the architecture known as mixtures of experts (MEM). Here we suggest a mixture which blends several autoregressive models. This study focuses on some theoretical foundations of the prediction problem in this context. More precisely, it is demonstrated that this model is a universal approximator, with respect to learning the ...

In Monte Carlo simulations of lattice field theory with a θ term, one confronts the complex weight problem, or the sign problem. This is circumvented by performing the Fourier transform of the topological charge distribution P (Q). This procedure, however, still causes the flattening phenomenon of the free energy, which prevents one from studying the phase structure. In order to work at this is...

The Rockefeller University Press $30.00 J. Exp. Med. www.jem.org/cgi/doi/10.1084/jem.20072682 Cite by DOI: 10.1084/jem.20072682 1 of 11 Protective immunity elicited by T cell – dependent antigens may last for decades without further exposure to the immunizing antigen ( 1, 2 ), and the memory B (B Mem ) cells serve an important role in sustaining humoral immunity. A defi ning characteristic of B...

Background: Carbapenems (CAR), colistin (CST), and tigecycline (TGC) alone or in combination therapy has become the last-resort antibiotics for treating infections caused by multidrug resistant (MDR) bacteria. However, resistance to these reserve antibiotics are increasingly being reported worldwide. Hence, the quest to find other agents that will synergistically restore the efficacy of these a...

BACKGROUND Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown to be fully effective. In order to solve this issue, polylactic-co-glycolic (PLGA) nanoparticles could be a suitable solution to increase drug's action on the target site as well as decrease adverse effects. For these reason, Memantine was loaded in biodegradable PLGA nanoparticles, produced by double ...

To profit from alternate visualization techniques and contributions from a large public domain user community, an interface of AVS/Express to the MEM-COM data management environment was created. Our interface allows single-block and multi-block configurations, structured and unstructured datasets, steady or transient solutions.

The MEM mode is a nonce-based enciphering mode of operation proposed by Chakraborty and Sarkar, which was claimed to be secure against symmetric nonce respecting adversaries. We show that this is not correct by using two very simple attcks. One attack need one decryption and one decryption queries, and the other only need one encryption query.

BACKGROUND Urine dipstick testing for ketones is widely used when diabetic ketoacidosis (DKA) is suspected in patients with hyperglycaemia. If urinary ketones are positive, patients are referred for further management--often inappropriately, as the test is a poor surrogate for plasma ketones. Plasma beta-hydroxybutyrate (β-OHB) levels>3 mmol/L are diagnostic of DKA, while levels<1 mmol/L are in...

Neonatal sepsis and meningitis (NSM) remains a leading cause worldwide of mortality and morbidity in newborn infants despite the availability of antibiotics over the last several decades. E. coli is the most common gram-negative pathogen causing NSM. Our previous studies show that α7 nicotinic receptor (α7 nAChR), an essential regulator of inflammation, plays a detrimental role in the host defe...

Entropy is a measure of probabilistic uncertainty. In 1957, E.T. Jaynes introduced his idea of the principle of Maximum Entropy. This idea states that by finding a distribution with the maximum entropy, one maximizes the uncertainty constrained to the given information. In essence, this involves using all of the known information, and assuming nothing about the distribution. In this report, we ...