Traumatic Brain injury (TBI) is one of the most common causes of death and disability worldwide, with recent interest in the use of cholinomimetics in the treatment of TBI patients for cognitive impairments. Our patient who suffered TBI was started on a trial of an acetylcholinesterase inhibitor (Donepezil) for five weeks. Cognitive and memory testing with the Mini-Mental State Examination (MMS...

objectives: the prospective and retrospective memory questionnaire (prmq) developed by smith (2000) and consists of a series of questions about memory weakness that can be encountered anyone in everyday life. the self-reported questionnaire has 16 items that assessing of prospective and retrospective memory problems in everyday life and the aim of the present research was to examine the investi...

BACKGROUND Mild traumatic brain injury (TBI) or concussion is common in many sports. Today, neuropsychological evaluation is recommended in the monitoring of a concussion and in return-to-play considerations. To investigate the sensitivity of neuropsychological assessment, we tested amateur boxers post bout and compared with controls. Further the relationship between neuropsychological test res...

Memory impairment is a disabling condition and one of the most common complaints affecting patients with neurological deficits. Neurological disorders, such as Alzheimer disease (AD), Parkinson disease (PD), traumatic brain injury (TBI), and epilepsy, as well as normal aging, can lead to problems in declarative, working, and episodic memory. These impairments often place significant psychologic...

The design and development of a motivational embodied conversational agent for brain injury rehabilitation is discussed. Results initial prototype implementation, alpha beta testing phases are presented. Key aspects identified during included supporting user engagement via personalization choice-making; integrating behaviour change principles into dialogues; addressing clinical needs cognitive ...

Introduction: Existing research and treatment for brain injured adults uses cognitive rehabilitation to address memory deficits including compensatory and remedial techniques. Electronic devices such as the Neuropage and palm top computers are effective in compensating for memory deficits. However, these require the user to be trained and proficient in their use. This exploratory study investig...

this is an observational case series study on penetrating trauma admissions in three teaching hospitals in tehran from 1996 to 1997. in order to describe the epidemiology and determine the ways of improving treatment of penetrating injuries, we selected 410 patients with penetrating injuries and injury severity scores (iss) of more than 7 (the maximum iss is 75) out of 3580 trauma patients, hos...

A synthetic peptide with antisecretory activity, antisecretory factor (AF)-16, improves injury-related deficits in water and ion transport and decreases intracranial pressure after experimental cold lesion injury and encephalitis although its role in traumatic brain injury (TBI) is unknown. AF-16 or an inactive reference peptide was administrated intranasally 30 min following midline fluid perc...

Head injury accounts for a quarter of trauma related deaths but for a much larger proportion of lifelong disability. With the rise in high speed traffic, the number of high velocity injuries, resulting in mainly diffuse head trauma has also increased drastically. The cognitive and behavioral sequelae of closed head injury may be extensive and diverse -ranging from cognitive deficits to psychiat...