Urinary excretion of ultraviolet-light-absorbing end products of metabolism was studied in mentally retarded children and schizophrenic adults. Excretion of the major end product of pyrimidine metabolism, pseudouridine (5-ribosyluracil), and one of the catabolic derivatives of nicotinic acid, N -methyl-2-pyridone-5-carboxamide, were both found to be depressedin more than half the mentally retar...

OBJECTIVE The metaphase of 21 severely mentally retarded patients were studies to assess the role of satellite association in the etiology of mental retardation. METHODS Peripheral blood culture, chromosome harvesting and study scoring were conducted according to standard methods. RESULTS Considered as a whole the results indicate that there is a significant increase in the frequency of sat...

Abstract Creating suitable classrooms that can meet the educational needs of mentally-retarded students is vitally important. The present study explores the effect of three physical characteristics of classroom environment on the creativity of educable mentally-retarded children: window view, window size, and classroom size. The participants, one hundred 9-to-11-year-old girl students, took th...

We describe three unrelated patients with apparently identical interstitial deletions of the segment (18) (q12.2q21.1). They were a short and markedly mentally retarded 5 year old girl, a macrocephalic and obese 2 1/2 year old boy with moderate mental retardation, and a macrocephalic, severely mentally retarded 5 year old boy. Findings common to all five liveborn patients so far identified as c...