DFT calculations and X-ray crystallography were used to directly compare the reactivity of the convex carbon surfaces of C20H10-corannulene and the C60-fullerene toward the diruthenium(I,I) metal cluster.

a pvc membrane electrode based on 1-[({[(butylsulfunyl)carbothioyl]disulfanyl} carbothioyl)sulfanyl]butane as a suitable ion carrier for determination of lanthanum(iii) ion was prepared. this electrode revealedsuch a good selectivity toward la3+ ion over a wide variety of other metal ions. some experimental parametersuch as membrane composition, nature, and amount of plasticizer, the amount of ...

To dissect the effects of the nucleotide-binding and catalytic metal ions on DNA polymerase mechanisms for DNA repair and synthesis, aside from the chemical reaction, we investigate their roles in the conformational transitions between closed and open states and assembly/disassembly of the active site of polymerase /DNA complexes before and after the chemical reaction of nucleotide incorporatio...

Introduction etal-on-metal bearings for hip replacement are gaining popularity as an alternative to the most widely used bearing couple of metal on polyethylene. The recent resurgence of hip resurfacing with the socalled third and fourth generations of hip resurfacing arthroplasty devices has played a substantial role in the wider use of metal-on-metal bearings. Concerns about the wear of polye...

reaction, which occurs under mild conditions and at low concentrations of reactants, is absolutely dependent on the presence of bivalent metal ions, and is stimulated by univalent metal ions. The most effective bivalent metal ion was found to be Ca++. When Mn++ ion was used to satisfy the bivalent metal ion requirement, the most effective univalent metal ion was found to be Kf. The reaction was...

Binding of a transition metal ion to specific sites in concanavalin A induces the formation of specific Ca(2+) ion-binding sites. Sites for binding alpha-methyl d-glucopyranoside exist only when a transition metal ion and Ca(2+) ion are bound.

The field of de novo protein design, though only two decades old, has already reached the point where designing and selecting novel proteins that are functionally active has been achieved several times. Here we review recently reported de novo functional proteins that were developed using various approaches, including rational design, computational optimization, and selection from combinatorial...

To dissect the effects of the nucleotide-binding and catalytic metal ions on DNA polymerase mechanisms for DNA repair and synthesis, aside from the chemical reaction, we investigate their roles in the conformational transitions between closed and open states and assembly/disassembly of the active site of polymerase beta/DNA complexes before and after the chemical reaction of nucleotide incorpor...

Class B beta-lactamases or metallo-beta-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of beta-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. There are no clinically useful inhibitors against MBLs which are responsible for the resistance of some bacteria to antibiotics. There are two metal-ion binding sites that have different zinc ligands ...