BACKGROUND At present, there is no standard of treatment using systemic high-dose corticosteroids in cases of pregnant women with Vogt-Koyanagi-Harada (VKH) disease. Although high-dose systemic corticosteroid treatment is often used for VKH disease during pregnancy, it also poses a risk to the fetus. FINDINGS A 29-year-old woman in the 34th week of pregnancy experienced bilateral metamorphops...

PURPOSE To report an unusual case of central serous chorioretinopathy (CSC), presenting as bilateral and multifocal isolated serous retinal pigment epithelium detachments (RPEDs) following corticosteroid treatment. METHODS An otherwise healthy 39-year-old man was evaluated for visual loss following blunt trauma of his right eye (RE). The patient underwent complete bilateral ophthalmologic exa...

A 34-year-old man with history of stress presented to the emergency department with blurred vision in the left eye for the past week. There has been no vision change in his right eye. The vision acuity of the left eye was 20/100. The fundus examination revealed a localized serous detachment of the macula (A). The fluorescein angiography (B) and the ocular coherence tomography (OCT) (C) confirme...

Background. Tilted disc syndrome (TDS) is a congenital anomaly characterized by "tilting" of the optic disc tipycally associated with myopic astigmatism, visual field defect, inferior staphyloma, and retinal pigment epithelium atrophy. Associated complications such as macular serous neuroretinal detachment are well described; however, ideal therapy for such complication is unknown. Methods. One...

Direct exposure to intensive visible light can lead to solar retinopathy, including macular injury. The signs and symptoms include central scotoma, metamorphopsia, and decreased vision. However, there have been few studies examining retinal injury due to intensive light stimulation at the cellular level. Neural network arrangements and gene expression patterns in zebrafish photoreceptors are si...

OBJECTIVE To describe the clinical and genetic findings in a family with a peculiar autosomal dominant macular dystrophy with peripheral deposits. METHODS All family members underwent an ophthalmic examination, and their genomic DNA was screened for mutations in the human retinal degeneration slow (peripherin/RDS) and rhodopsin genes. In selected cases, fluorescein angiography and electrophys...

A 21 year old male patient reported in 2003 with complaint of diminution of vision in left eye since 1 month. Best corrected visual acuity OD was 20/20 and 20/120 OS. Fundus evaluation revealed angioid streaks in both eyes with scarred Choroidal neovascularization (CNV) in left eye [Fig. 1]. He was followed up regularly at intervals of 3 months. In 2010, he noticed blurring of vision in the rig...

PURPOSE The phosphoinositide kinase, FYVE finger containing (PIKFYVE) gene has been identified as a gene responsible for fleck corneal dystrophy (FCD). The purpose of this study is to report a novel mutation of the PIKFYVE gene in a Japanese patient with fleck corneal dystrophy. METHODS Slit-lamp microscopy, corneal topography, and optical coherence tomography were performed for the clinical ...

Purpose. Myopic macular holes can be difficult to close with surgery and are frequently associated with retinal detachment. We report on a case of a macular hole in a severely myopic eye that underwent spontaneous closure. Methods. An observational case study. Results. A 55-year-old female was referred to Ophthalmology for a central scotoma and metamorphopsia in the right eye. Visual acuity was...

All RDs are accompanied by some loss of visual function but this will vary depending upon the type of detachment, its size, and retinal location, making it difficult to ascribe one set of symptoms to the condition (Box 71.3). Diagnosing RD is complex with many qualifications. Abnormal vision is the only reliable symptom of RD. But the types of abnormal vision are large and varied: light flashes...