OBJECTIVES To determine the sensitivity, accuracy, and clinical relevance of intra-operative examination of sentinel lymph nodes in breast cancer management. DESIGN Retrospective study. SETTING Private anatomical pathology practice. PARTICIPANTS Three hundred breast cancer patients who underwent axillary sentinel lymph node biopsies for intra-operative assessment between January 2004 and ...

Breast cancer can present with metastatic disease initially or as a systemic relapse despite seemingly adequate initial treatment. We report a case of suspected metastatic breast cancer to an intraabdominal lymph node based on imaging, which was subsequently confirmed by tissue sampling at the time of endoscopic ultrasound (EUS). While previous studies have shown the utility of EUS in the diagn...

BACKGROUND Accurate diagnosis of lymph node metastasis is crucial in treatment planning for cancer patients. Despite the use of various parameters, making correct diagnosis of a small metastatic or a hyperplastic benign node is still a challenge. In this study, we evaluated the feasibility of detecting lymph node metastasis using a new ultrasmall superparamagnetic iron oxide particle, PJY10, in...

10-14 regional lymph nodes, nodal staging in stage III colorectal cancer, which is solely based on the number of metastatic lymph nodes, would be inaccurate in certain circumstances. Recently, the metastatic lymph-node ratio has been suggested as an alternative tool for nodal staging in stage III colorectal cancer [2-4]. Also, after preoperative chemoradiation therapy in rectal cancer patients,...

UNLABELLED The removal of level II, III, and IV metastases has gained importance in the treatment of squamous cell carcinomas (SCC) of the neck and larynx. This study assessed the possibility of removing level II and level III metastases only, given the low likelihood of occurrence of metastatic lymph nodes on level IV in SCCs of the larynx. OBJECTIVE This study aimed to analyze the prevalenc...

lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...

abstract castleman disease or giant node hyperplasia is a rare disorder of the lymphoid tissue most often involving the mediastinal lymph nodes. we report a case of localized retroperitoneal hyaline-vascular type of castleman disease. a 35-year old woman presented with mild epigastric pain with radiation to the back. amild anemia was the only abnormal associated finding. abdominal ultrasound an...

The aim of the study was to determine if age plays a role in the size of metastatic lymph nodes in elderly patients with squamous cell carcinoma of the head and neck (HNSCC). In 180 HNSCC patients with metastatic lymph nodes, largest metastatic lymph node (SMLN), diameter of metastatic deposit (DMD), and the ratio of non-metastatic lymphoid tissue to the size of largest metastatic lymph node (R...

BACKGROUND Lymph node metastasis of hepatocellular carcinoma is rare, and lymph nodes located on hepatic hilar and hepatoduodenal ligaments are primary targets. Metastasis to a mesocolic lymph node has not been reported previously. CASE REPORT A 65-year-old woman with liver cirrhosis underwent primary resection of hepatocellular carcinoma. Two and a half years later, tumor marker levels increas...

CONTEXT Uncertainty remains about the extent and indications for inguinal lymphadenectomy in penile cancer, a procedure known for relatively high morbidity. Several attempts have been made to develop strategies which can improve the diagnostic quality and reduce the morbidity of the management of inguinal lymph nodes in penile cancer. OBJECTIVE To analyse the existing published data on the su...