The European and United States Pharmacopoeia demand a noninferiority study on the detection of microorganisms when an alternate qualitative microbiological method is intended to replace compendial method. However, without imposing any modeling assumptions or constraints, studies require large numbers test samples for proposed criterion 0.7 higher each microorganism. When we can assume that accu...

Diagnosis of vaginal discharge is frequently performed in an empirical way, leading to inadequate treatment. This study tested the accuracy of a self-collection kit for microbiological study of the vaginal content. One hundred and forty-two women of Family Health Program units in Niterói and Piraí cities were enrolled in order to have their vaginal content studied. A brief explanation and a sel...

OBJECTIVE Microbiological examination of donated human cardiac tissue is a necessary procedure for Heart Valve Banks to determine the biological safety of preserved allografts. Test protocols must be validated to prevent false-negative outcomes that pose a risk of infection to recipients of the tissue. The Heart Valve Bank in Rotterdam evaluated a validated, alternative entry test for donated t...

background: the main stay of primary and secondary prevention of periodontal diseases has been the control of supra gingival plaque. acceptable plaque control by mechanical means is difficult to achieve by most individuals, so mouth rinses represent one form of attack on oral microbes and the malodor. chlorhexidine (chx) is a broad‑spectrum antimicrobial agent known to cause damage to the cell ...

BACKGROUND Community-acquired pneumonia (CAP) remains an important cause of morbidity and mortality. Polymerase chain reaction (PCR) has been shown to be more sensitive than current standard microbiological methods and, therefore, may improve the accuracy of microbiological diagnosis for patients with CAP. METHODS Conventional detection techniques and multiplex real-time PCR for atypical bact...

BACKGROUND To investigate the influence of chemical and microbiological methods of caries induction on bond degradation of adhesive systems to primary dentin. METHODS Flat dentin surfaces from 36 primary molars were assigned to three groups (n = 12) according to method to induce caries-affected dentin: (1) control (sound dentin); (2) pH-cycling; and (3) microbiological caries induction model....

Introduction: Halvi is a traditional dairy product made from sheep milk in Mazandaran province, especially in the mountainous areas of Noor and Kojur. The fungus used in the preparation of Halvi is Auricularia auricula-judae. The present study aimed to investigate the chemical composition and microbiological properties of Halvi samples produced in various regions in No...