BACKGROUND Mitral valve prolapse (MVP) is accompanied by mental disorders including anxiety, which has similar presentations as MVP. It is hypothesised that treatment of anxiety might reduce the symptoms of MVP. OBJECTIVE The aim of this study was to assess the clinical and echocardiographic effects of fluoxetine administration in patients with MVP and anxiety. METHODS This randomized clini...

Systolic anterior motion (SAM) of the mitral valve in the absence of asymmetric septal hypertrophy or concentric left ventricular hypertrophy has been reported in several conditions. In this report we describe the clinical and echocardiographic findings in 15 patients who demonstrated SAM without associated organic heart disease (group 1, 10 patients) or in association with mitral valve prolaps...

Typical patients with MVP, especially global leaflet prolapse or Barlow type prolapse, have prominent MV annular dilatation with only modest LV dilatation. This discrepancy suggests that patients with MVP and annular dilatation frequently have basal predominance of LV dilatation (Figure 1). Predominantly, basal LV dilatation may cause greater systolic wall tension in the LV base compared with t...

A prominent filling defect was depicted on a radionuclide ventriculogram in a patient with mitral regurgitation. This defect was later shown, by cardiac ultrasound, to be due to mitral valve prolapse into the left ventricle during diastole. This case illustrates that mitral valve prolapse should be added to the list of clinical entities that can result in an intraventricular defect on a radionu...

The association of dysrhythmias with mitral valve prolapse in pediatric patients was investigated by graded treadmill exercise testing and 24-hour ambulatory ECG monitoring. Twenty-six unselected patients with a clinical diagnosis of mitral valve prolapse confirmed by echocardiography or angiocardiography or both were studied. On 24-hour ambulatory ECG monitoring, six patients (23%) had potenti...

we present a very rare case of partially unroofed coronary sinus without persistent left superior vena cava in a 74 years old female with a history of hypertension, severe myxomatous bileaflet mitral valve prolapse with severe eccentric mitral regurgitation which was diagnosed during cardiac surgery.

Real-time two-dimensional sector sanning was used to analyse mitral valve motion in 4 normal subjects and 6 patients with previously diagnosed mitral valve prolapse syndromes. The normal mitral valve leaflets remain apposed for the duration of systole, and open abruptly with the onset of diastole. During diastole the leaflets are parallel to each other and only the distal ends tend to 'float' c...

Mitral valve prolapse: harbinger of death or variant of normal? It is 21 years since Barlow and colleagues recognised prolapse of the posterior leaflet of the mitral valve during angiography and related this to the auscultatory phenomena of the late systolic click and murmur.' Two years earlier in 1961 Reid, also from South Africa, had first proposed that the features were of mitral rather than...

Familial prevalence of mitral valve prolapse in a Chinese population was determined in 22 propositi of whom 10 had straight back (group A), three had abnormally high metacarpal index (group B), and nine had neither (group C). Of 71 (32 male and 39 female subjects) first degree relatives screened, mitral valve prolapse was found in 19 (seven male and 12 female subjects) (26.8%). The familial pre...

Using transesophageal echocardiography, cardiac structures can be imaged with high resolution. The aim of our study was to evaluate whether transesophageal echocardiography is superior in detecting mitral valve prolapse and other cardiac abnormalities compared with transthoracic echocardiography in an age-matched control group and in young patients with cerebral ischemic events (patient group)....